Methyltetrazine-Labeled Functionalized Magnetic Beads are magnetic particles modified with methyltetrazine groups, enabling rapid and selective conjugation via inverse electron-demand Diels–Alder (IEDDA) click reactions with trans-cyclooctene (TCO)-labeled biomolecules. This copper-free, bioorthogonal chemistry is ideal for capturing or immobilizing TCO-tagged proteins, peptides, or other targets under mild, physiological conditions. The magnetic core allows for quick and efficient separation, making these beads highly suitable for purification, enrichment, and targeted labeling workflows.
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