Quantum Dots
Vector Laboratories R&D
Unlock new potential in quantum dots fluorescence and further expand their applications in research and medicine.
Unlock new potential in quantum dots fluorescence and further expand their applications in research and medicine.
BioDesign click chemistry crosslinkers are designed for versatility and can be utilized in an assortment of applications.
This guide explains how to select maleimide crosslinkers on linear and multi-arm dPEG® linkers, with pH best practices, thiol/amine selectivity, solubility notes, and examples for ADCs, lipids, and proteins.
In the first of our three part series on Bioconjugation, we’ll be exploring what’s involved, how it enables life science research, the challenges associated with it, and the excitement in future work.
In the previous section, we discussed the methods of bioconjugation. And the marriage of a biomolecule and a small molecule has given rise to various modalities commonly used in biomedical research. Here, we focus on the applications in the fields of therapeutics, diagnostics, protein-protein interactions, and nanotechnology.
With knowledge of the applications that bioconjugation can play into, we finish by highlighting its key advantages and critical uses. While the applications are much broader than what we summarize here, we can deduce common threads between these methods.
The body’s autoimmune response has been leveraged by cancer researchers to propel immunotherapy tools into clinical use. Although the main focus has been on the ability of T-cells to fight cancer cells, the involvement of tumor-infiltrating B-cells is also becoming evident. Tumor-infiltrating B lymphocytes (TIL-Bs) are produced in much higher amounts in various cancers than in healthy tissues, which highlights their positive prognostic value (1). However, their exact role in cancer remains controversial, with the demonstration of both positive and negative impacts.
Multiplexing has revolutionized immunostaining workflows. It allows the simultaneous detection of multiple targets in the same tissue section and empowers scientists to gather more data while sparing precious samples. But issues with cross-reactivity between reagents can hinder the ability to perform simultaneous double or triple staining. When these issues arise, scientists can use the VectaPlexÔ Antibody Removal Kit to do multiple rounds of labeling and perform multiplexing experiments.
The body’s autoimmune response has been leveraged by cancer researchers to propel immunotherapy tools into clinical use. Although the main focus has been on the ability of T-cells to fight cancer cells, the involvement of tumor-infiltrating B-cells is also becoming evident. Tumor-infiltrating B lymphocytes (TIL-Bs) are produced in much higher amounts in various cancers than in healthy tissues, which highlights their positive prognostic value (1). However, their exact role in cancer remains controversial, with the demonstration of both positive and negative impacts.
Antibodies are the epitome of simple yet powerful science tools. Made of just 4 peptides, they never cease to help scientists unravel the intricacies of the microscopic world
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