
AZDye™ 488 Cadaverine is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be employed as a polar tracer and as a reactive dye for labeling proteins via a carboxylic acid moiety.
AZDye™ 488 is a water-soluble, bright, green-fluorescent dye with excitation ideally suited to the 488 nm laser line. Its green fluorescence is pH independent from pH 4 to pH 10. AZDye™ 488 can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates which are often used for generation of stable signals in imaging and flow cytometry.
AZDye™ 488 Cadaverine is structurally identical to Alexa Fluor® 488 Cadaverine. Its absorption/emission spectra is a perfect match to spectra of many other fluorescent dyes based on sulfonated rhodamine 110 core, including CF®488 Dye, DyLight® 488 and Alexa Fluor® 488.
| Unit Size | 1 mg, 5 mg, 25 mg, 100 mg |
|---|---|
| Reactivity | Aldehydes, carboxylic acid, ketones |
| Abs/Em Maxima | 494/517 nm |
| Extinction coefficient | 73,000 cm-1M-1 |
| Solubility | Water, DMSO, DMF |
| Spectrally similar dyes | Alexa Fluor® 488, DyLight® 488, Fluorescein, Oregon Green 488 |
| Molecular weight | 618.63 (protonated) |
| Storage Conditions | -20°C. |
| Shipping Conditions | Ambient temperature |

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