Carboxyl Reactive

Carboxyl-Reactive Linkers for High-Density PEGylation

Carboxyl-reactive uniform branched PEG modifiers are branched polyethylene glycol (PEG) molecules functionalized with groups such as amines or hydrazides that selectively react with carboxyl groups on biomolecules to form stable amide or hydrazone bonds.

These modifiers enable site-specific conjugation to proteins, peptides, or other carboxyl-containing compounds, enhancing solubility, stability, and biocompatibility. Their uniform branched structure provides multiple functional arms, making them ideal for multivalent conjugation in drug delivery, diagnostics, and biotherapeutic applications.