Heterobifunctional Amine and Thiol Reactive Uniform PEG Cross-Linkers are polyethylene glycol (PEG)-based molecules engineered with two distinct reactive groups—typically an NHS ester for amine conjugation and a maleimide or similar moiety for thiol conjugation.
This configuration enables the site-specific and stable cross-linking of biomolecules containing primary amines (e.g., lysine residues) and sulfhydryl groups (e.g., cysteine residues).
The uniform PEG backbone provides solubility, biocompatibility, and spatial flexibility, making these cross-linkers ideal for applications in protein engineering, drug delivery, and bioconjugation.
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