Custom Antibody Services
A leading provider of custom antibody sequencing, engineering, production, and purification services, we serve biotech innovators across therapeutic, diagnostic, and research applications. Our mission is to deliver engineered confidence—ensuring every antibody we produce is built on scientific rigor, transparency, and fit-for-purpose quality.
Antibody Engineering Expertise
Confidence engineered into every antibody.
- Successful production of 200+ different antibody formats
- Specialization in complex constructs including bispecifics, scFvs, and fragments
- Collaborative approach to develop the antibody best suited to your needs
Tailored Solutions
Every process is tailored to your molecule—not the other way around
- Customized workflow, from design to purification, based on the unique characteristics of each antibody
- 45+ purification routes across a dozen platforms to elicit highly pure antibodies
Rigorous Quality Controls
Quality built in, not bolted on.
- Workflows designed with quality in mind, not just QC at the end
- Built in checks throughout the process to go beyond “good enough”
- SEC and CE-SDS included as standard practice
Engineered recombinant antibodies developed for our reagents catalog
Hybridomas sequenced
Successful antibody humanization projects
Different antibody formats produced
Antibody Sequencing
It starts with a sequence.
Knowing your hybridoma or antibody protein sequence is crucial for the security and continuation of your antibody production. Our antibody sequencing services include Next generation Sequencing of hybridoma cells and de novo sequencing of purified antibody protein. Sequencing can be performed as a stand-alone activity, or as the first step toward antibody engineering and transient serum-free expression. Whether it is a hybridoma or purified monoclonal antibody protein, Absolute Antibody offers industry-leading sequencing services to help safeguard your invaluable antibody.
Why Sequence Your Antibodies?
- Protect against loss, contamination or genetic drift
- Secure your supply chain
- Enable antibody engineering and recombinant production
- Patent your antibody
Hybridoma Sequencing Service
- Novel NGS approach to high-throughput sequencing
- Identifies all heavy chain and light chain sequences and quantifies their relative abundance
- Compatible with any species and isotype
Antibody Protein Sequencing Service
- Sequence from purified monoclonal antibody when hybridoma is not available
- Combines mass spectrometry with high accuracy de novo peptide sequencing and recombinant expression
Our hybridoma sequencing method – The mRNA transcriptome is obtained from the hybridoma, and random hexamers are used to generate a cDNA library. This is fragmented and undergoes paired-end sequencing. The sequencing reads are assembled into contigs, from which antibody transcripts are identified based on homology.
Antibody Engineering
Engineered Confidence. Built Around Your Molecule.
Explore our royalty-free antibody engineering capabilities.
Periodic Table of Antibodies
Explore 180+ antibody formats in our interactive Periodic Table of Antibodies
Antibody Production
Scalable expression tailored to your molecule.
Absolute Antibody’s expression platforms rapidly produce high-quality, animal-free recombinant antibodies in HEK or CHO cells. By utilizing a serum-free mammalian transient expression system, our production service offers a faster, more affordable alternative to stable cell line generation. This robust platform has proven success in manufacturing recombinant antibodies in any species, isotype, or format with high purity and low endotoxin levels.
Scalability matters, which is why we offer a microgram-to-gram range of expression capabilities. From small-scale production, perfect for lead discovery candidate selection, to large-scale production, our expression services are flexible to your needs.
Antibody Expression
Current Promotions
10% off
one project
20% off
two projects
30% off
three or more projects
50% off
discount for off-the-shelf isotype control catalog antibodies.
Terms and conditions:
This offer is valid for new production projects through Dec 31, 2025. Limitations may apply when combining with existing offers and/or discounts. Final price and discount will be determined and reflected on the project quotation. 50% discount for off-the-shelf isotype control catalog antibodies is valid only when the isotype control antibody order is placed with any custom antibody production projects. Absolute Antibody, a Vector Laboratory company, reserves the rights to change or modify this promotion.
