Mono Sulfone – VectorLabs https://staging.vectorlabs.com From linker design and synthesis, bioconjugated design and manufacturing, biomolecule labeling and functionalization, and detection system and solutions, our team is here to help you move forward, with impact. Wed, 22 Oct 2025 17:08:57 +0000 en-US hourly 1 https://wordpress.org/?v=6.9 https://staging.vectorlabs.com/wp-content/uploads/2024/11/V-favicon-02-100x100.png Mono Sulfone – VectorLabs https://staging.vectorlabs.com 32 32 Mono-sulfone Acid https://staging.vectorlabs.com/products/mono-sulfone-acid/ Tue, 19 Sep 2023 20:04:52 +0000 https://staging.vectorlabs.com/?post_type=product&p=22412 Description

Mono-sulfone is a thiol-specific labeling reagent that undergo alkylation to generate a thio-ether bond between the protein and mono-sulfone activated reagent. Once mono-sulfone reagent is conjugated to a protein or peptide, exchange reactions leading to deconjugation can be easily avoided by treating the conjugate with a mild reducing agent in a way analogous to the process used for conjugation reactions involving reductive amination.

Specifications

Unit Size 1000 mg, 5 g
Molecular weight 332.37
Chemical composition C17H16O5S
CAS N/A
Solubility DMSO, DMF
Purity >95% (HPLC)
Appearance Grey solid
Storage Conditions -20°C. Desiccate
Shipping Conditions Ambient temperature

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Description

Mono-sulfone is a thiol-specific labeling reagent that undergo alkylation to generate a thio-ether bond between the protein and mono-sulfone activated reagent. Once mono-sulfone reagent is conjugated to a protein or peptide, exchange reactions leading to deconjugation can be easily avoided by treating the conjugate with a mild reducing agent in a way analogous to the process used for conjugation reactions involving reductive amination.

Specifications

Unit Size1000 mg, 5 g
Molecular weight332.37
Chemical compositionC17H16O5S
CASN/A
SolubilityDMSO, DMF
Purity>95% (HPLC)
AppearanceGrey solid
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

Documents

Selected References

  1. Badescu, G., et al. (2014). A New Reagent for Stable Thiol-Specific Conjugation. Bioconjug. Chem., 25(3), 460-9. [PubMed]

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