Azide – VectorLabs https://staging.vectorlabs.com From linker design and synthesis, bioconjugated design and manufacturing, biomolecule labeling and functionalization, and detection system and solutions, our team is here to help you move forward, with impact. Wed, 22 Oct 2025 17:18:25 +0000 en-US hourly 1 https://wordpress.org/?v=6.9 https://staging.vectorlabs.com/wp-content/uploads/2024/11/V-favicon-02-100x100.png Azide – VectorLabs https://staging.vectorlabs.com 32 32 Azido-dPEG®₃₆-OH https://staging.vectorlabs.com/products/azido-dpeg36-oh/ Sat, 24 Feb 2024 02:11:33 +0000 https://staging.vectorlabs.com/?post_type=product&p=36431 Azido-dPEG®36-OH (Azido-dPEG®36-alcohol), product number QBD-10544, is a click chemistry reagent used to modify surfaces and biomolecules or to crosslink with other surfaces or biomolecules in supramolecular construction. This product consists of an azide and a terminal hydroxy group separated by a long (108 atoms), single molecular weight, discrete-length polyethylene glycol (dPEG®) chain. The terminal azide reacts in copper(I)-catalyzed, ruthenium-catalyzed, and strain-promoted azide-alkyne cycloaddition reactions (CuAAC, RuAAC, and SPAAC, respectively). If left unmodified, the alcohol group increases the water solubility and hydrodynamic volume of molecules and surfaces to which it is conjugated. Modifying the alcohol with a reactive group such as chloride, tosylate, or mesylate allows Azido-dPEG®36-OH to function as a crosslinker through subsequent chemical manipulations.

As a click chemistry reagent, azido-dPEG®36-OH can participate in CuAAC, RuAAC, and SPAAC reactions. Because Vector Laboratories' dPEG® products are amphiphilic, these reactions can occur almost equally well in water or organic solvents. The primary alcohol group on the opposite end of the linker can be used as a neutrally charged functional group. In this function, the alcohol enhances the water solubility of the conjugate molecule. Alternatively, the alcohol group can be functionalized with reactive groups and used to modify the conjugate further. Thus, azido-dPEG®36-OH can be used in conjugations with biomolecules where organic solvents may damage the conjugate target. This product was published in a 2014 paper demonstrating high-throughput modifications of siRNA via CuAAC.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 1628.92; single compound
Chemical formula C₇₂H₁₄₅N₃O₃₆
CAS
73342-16-2
Purity > 97%
Spacers
dPEG® Spacer is 108 atoms and 129.7 Å
Shipping
Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post Azido-dPEG®₃₆-OH appeared first on VectorLabs.

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Description

Azido-dPEG®36-OH (Azido-dPEG®36-alcohol), product number QBD-10544, is a click chemistry reagent used to modify surfaces and biomolecules or to crosslink with other surfaces or biomolecules in supramolecular construction. This product consists of an azide and a terminal hydroxy group separated by a long (108 atoms), single molecular weight, discrete-length polyethylene glycol (dPEG®) chain. The terminal azide reacts in copper(I)-catalyzed, ruthenium-catalyzed, and strain-promoted azide-alkyne cycloaddition reactions (CuAAC, RuAAC, and SPAAC, respectively). If left unmodified, the alcohol group increases the water solubility and hydrodynamic volume of molecules and surfaces to which it is conjugated. Modifying the alcohol with a reactive group such as chloride, tosylate, or mesylate allows Azido-dPEG®36-OH to function as a crosslinker through subsequent chemical manipulations.

As a click chemistry reagent, azido-dPEG®36-OH can participate in CuAAC, RuAAC, and SPAAC reactions. Because Vector Laboratories’ dPEG® products are amphiphilic, these reactions can occur almost equally well in water or organic solvents. The primary alcohol group on the opposite end of the linker can be used as a neutrally charged functional group. In this function, the alcohol enhances the water solubility of the conjugate molecule. Alternatively, the alcohol group can be functionalized with reactive groups and used to modify the conjugate further. Thus, azido-dPEG®36-OH can be used in conjugations with biomolecules where organic solvents may damage the conjugate target. This product was published in a 2014 paper demonstrating high-throughput modifications of siRNA via CuAAC.

Specifications

Unit Size100mg, 1000mg
Molecular Weight1628.92; single compound
Chemical formulaC₇₂H₁₄₅N₃O₃₆
CAS
73342-16-2
Purity> 97%
Spacers
dPEG® Spacer is 108 atoms and 129.7 Å
Shipping
Ambient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Application of Multivalent Interactions for Recognition Imaging and Delivery of Therapeutics. Saikat Manna. August 2016.

The post Azido-dPEG®₃₆-OH appeared first on VectorLabs.

]]> Azido-dPEG®₂₄-OH https://staging.vectorlabs.com/products/azido-dpeg24-oh/ Sat, 24 Feb 2024 02:11:32 +0000 https://staging.vectorlabs.com/?post_type=product&p=36422 Azido-dPEG®24-OH (Azido-dPEG®24-alcohol), product number QBD-10543, is a click chemistry reagent used to modify surfaces and biomolecules or to crosslink with other surfaces or biomolecules in supramolecular construction. This product consists of an azide and a terminal hydroxy group separated by a long (72 atoms), single molecular weight, discrete-length polyethylene glycol (dPEG®) chain. The terminal azide reacts in copper(I)-catalyzed, ruthenium-catalyzed, and strain-promoted azide-alkyne cycloaddition reactions (CuAAC, RuAAC, and SPAAC, respectively). If left unmodified, the alcohol group increases the water solubility and hydrodynamic volume of molecules and surfaces to which it is conjugated. Modifying the alcohol with a reactive group such as chloride, tosylate, or mesylate allows Azido-dPEG®24-OH to function as a crosslinker through subsequent chemical manipulations.

As a click chemistry reagent, azido-dPEG®24-OH can participate in CuAAC, RuAAC, and SPAAC reactions. Because Vector Laboratories' dPEG® products are amphiphilic, these reactions can occur almost equally well in water or organic solvents. Thus, azido-dPEG®24-OH can be used in conjugations with biomolecules where organic solvents may damage the conjugate target.

The primary alcohol group on the opposite end of the linker can be used as a neutrally charged functional group. In this function, the alcohol enhances the water solubility of the conjugate molecule. Alternatively, the alcohol group can be functionalized with reactive groups and used to modify the conjugate further.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 1100.29; single compound
Chemical formula C₄₈H₉₇N₃O₂₄
CAS
73342-16-2
Purity > 98%
Spacers
dPEG® Spacer is 72 atoms and 86.7 Å
Shipping
Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post Azido-dPEG®₂₄-OH appeared first on VectorLabs.

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Description

Azido-dPEG®24-OH (Azido-dPEG®24-alcohol), product number QBD-10543, is a click chemistry reagent used to modify surfaces and biomolecules or to crosslink with other surfaces or biomolecules in supramolecular construction. This product consists of an azide and a terminal hydroxy group separated by a long (72 atoms), single molecular weight, discrete-length polyethylene glycol (dPEG®) chain. The terminal azide reacts in copper(I)-catalyzed, ruthenium-catalyzed, and strain-promoted azide-alkyne cycloaddition reactions (CuAAC, RuAAC, and SPAAC, respectively). If left unmodified, the alcohol group increases the water solubility and hydrodynamic volume of molecules and surfaces to which it is conjugated. Modifying the alcohol with a reactive group such as chloride, tosylate, or mesylate allows Azido-dPEG®24-OH to function as a crosslinker through subsequent chemical manipulations.

As a click chemistry reagent, azido-dPEG®24-OH can participate in CuAAC, RuAAC, and SPAAC reactions. Because Vector Laboratories’ dPEG® products are amphiphilic, these reactions can occur almost equally well in water or organic solvents. Thus, azido-dPEG®24-OH can be used in conjugations with biomolecules where organic solvents may damage the conjugate target.

The primary alcohol group on the opposite end of the linker can be used as a neutrally charged functional group. In this function, the alcohol enhances the water solubility of the conjugate molecule. Alternatively, the alcohol group can be functionalized with reactive groups and used to modify the conjugate further.

Specifications

Unit Size100mg, 1000mg
Molecular Weight1100.29; single compound
Chemical formulaC₄₈H₉₇N₃O₂₄
CAS
73342-16-2
Purity> 98%
Spacers
dPEG® Spacer is 72 atoms and 86.7 Å
Shipping
Ambient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

High-Throughput Chemical Modification of Oligonucleotides for Systematic Structure-Activity Relationship Evaluation. Daniel Zewge, Francis Gosselin, David Matthew Tellers, Ian W. Davies, Vasant Jadhav, Sandhya S. Nerurkar, Yu Yuan, Jenny Li, W. Michael Flanagan, and Denise M. Kenski. Bioconjugate Chemistry. 2014, November 14, 2014. DOI” 10.1021/bc500453q.

The post Azido-dPEG®₂₄-OH appeared first on VectorLabs.

]]> Azido-dPEG®₈-OH https://staging.vectorlabs.com/products/azido-dpeg8-oh/ Sat, 24 Feb 2024 02:11:30 +0000 https://staging.vectorlabs.com/?post_type=product&p=36414 Azido-dPEG®8-OH (Azido-dPEG®8-alcohol), product number QBD-10542, is a click chemistry reagent used to modify surfaces and biomolecules or to crosslink with other surfaces or biomolecules in supramolecular construction. This product consists of an azide and a terminal hydroxy group separated by a medium-length (24 atoms), single molecular weight, discrete-length polyethylene glycol (dPEG®) chain. The terminal azide reacts in copper(I)-catalyzed, ruthenium-catalyzed, and strain-promoted azide-alkyne cycloaddition reactions (CuAAC, RuAAC, and SPAAC, respectively). If left unmodified, the alcohol group increases the water solubility and hydrodynamic volume of molecules and surfaces to which it is conjugated. Modifying the alcohol with a reactive group such as chloride, tosylate, or mesylate allows Azido-dPEG®8-OH to function as a crosslinker through subsequent chemical manipulations.

As a click chemistry reagent, azido-dPEG®8-OH can participate in CuAAC, RuAAC, and SPAAC reactions. Because Vector Laboratories' dPEG® products are amphiphilic, these reactions can occur almost equally well in water or organic solvents. Thus, azido-dPEG®8-OH can be used in conjugations with biomolecules where organic solvents may damage the conjugate target.

The primary alcohol group on the opposite end of the linker can be used as a neutrally charged functional group. In this function, the alcohol enhances the water solubility of the conjugate molecule. Alternatively, the alcohol group can be functionalized with reactive groups and used to modify the conjugate further.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 395.45; single compound
Chemical formula C₁₆H₃₃N₃O₈
CAS
352439-36-2
Purity > 98%
Spacers
dPEG® Spacer is 24 atoms and 29.5 Å
Shipping
Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post Azido-dPEG®₈-OH appeared first on VectorLabs.

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Description

Azido-dPEG®8-OH (Azido-dPEG®8-alcohol), product number QBD-10542, is a click chemistry reagent used to modify surfaces and biomolecules or to crosslink with other surfaces or biomolecules in supramolecular construction. This product consists of an azide and a terminal hydroxy group separated by a medium-length (24 atoms), single molecular weight, discrete-length polyethylene glycol (dPEG®) chain. The terminal azide reacts in copper(I)-catalyzed, ruthenium-catalyzed, and strain-promoted azide-alkyne cycloaddition reactions (CuAAC, RuAAC, and SPAAC, respectively). If left unmodified, the alcohol group increases the water solubility and hydrodynamic volume of molecules and surfaces to which it is conjugated. Modifying the alcohol with a reactive group such as chloride, tosylate, or mesylate allows Azido-dPEG®8-OH to function as a crosslinker through subsequent chemical manipulations.

As a click chemistry reagent, azido-dPEG®8-OH can participate in CuAAC, RuAAC, and SPAAC reactions. Because Vector Laboratories’ dPEG® products are amphiphilic, these reactions can occur almost equally well in water or organic solvents. Thus, azido-dPEG®8-OH can be used in conjugations with biomolecules where organic solvents may damage the conjugate target.

The primary alcohol group on the opposite end of the linker can be used as a neutrally charged functional group. In this function, the alcohol enhances the water solubility of the conjugate molecule. Alternatively, the alcohol group can be functionalized with reactive groups and used to modify the conjugate further.

Specifications

Unit Size100mg, 1000mg
Molecular Weight395.45; single compound
Chemical formulaC₁₆H₃₃N₃O₈
CAS
352439-36-2
Purity> 98%
Spacers
dPEG® Spacer is 24 atoms and 29.5 Å
Shipping
Ambient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post Azido-dPEG®₈-OH appeared first on VectorLabs.

]]> Azido-dPEG®₄-OH https://staging.vectorlabs.com/products/azido-dpeg4-oh/ Sat, 24 Feb 2024 02:11:29 +0000 https://staging.vectorlabs.com/?post_type=product&p=36406 Azido-dPEG®4-OH (Azido-dPEG®4-alcohol), product number QBD-10541, is a click chemistry reagent used to modify surfaces and biomolecules or to crosslink with other surfaces or biomolecules in supramolecular construction. This product consists of an azide and a terminal hydroxy group separated by a short (14 atoms), single molecular weight, discrete-length polyethylene glycol (dPEG®) chain. The terminal azide reacts in copper(I)-catalyzed, ruthenium-catalyzed, and strain-promoted azide-alkyne cycloaddition reactions (CuAAC, RuAAC, and SPAAC, respectively). If left unmodified, the alcohol group increases the water solubility and hydrodynamic volume of molecules and surfaces to which it is conjugated. Modifying the alcohol with a reactive group such as chloride, tosylate, or mesylate allows Azido-dPEG®4-OH to function as a crosslinker through subsequent chemical manipulations.

As a click chemistry reagent, azido-dPEG®4-OH can participate in CuAAC, RuAAC, and SPAAC reactions. Because Vector Laboratories' dPEG® products are amphiphilic, these reactions can occur almost equally well in water or organic solvents. Thus, azido-dPEG®4-OH can be used in conjugations with biomolecules where organic solvents may damage the conjugate target.

The primary alcohol group on the opposite end of the linker can be used as a neutrally charged functional group. In this function, the alcohol enhances the water solubility of the conjugate molecule. Alternatively, the alcohol group can be functionalized with reactive groups and used to modify the conjugate further.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 219.24; single compound
Chemical formula C₈H₁₇N₃O₄
CAS
86770-67-4
Purity > 98%
Spacers
dPEG® Spacer is 14 atoms and 15.3 Å
Shipping
Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post Azido-dPEG®₄-OH appeared first on VectorLabs.

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Description

Azido-dPEG®4-OH (Azido-dPEG®4-alcohol), product number QBD-10541, is a click chemistry reagent used to modify surfaces and biomolecules or to crosslink with other surfaces or biomolecules in supramolecular construction. This product consists of an azide and a terminal hydroxy group separated by a short (14 atoms), single molecular weight, discrete-length polyethylene glycol (dPEG®) chain. The terminal azide reacts in copper(I)-catalyzed, ruthenium-catalyzed, and strain-promoted azide-alkyne cycloaddition reactions (CuAAC, RuAAC, and SPAAC, respectively). If left unmodified, the alcohol group increases the water solubility and hydrodynamic volume of molecules and surfaces to which it is conjugated. Modifying the alcohol with a reactive group such as chloride, tosylate, or mesylate allows Azido-dPEG®4-OH to function as a crosslinker through subsequent chemical manipulations.

As a click chemistry reagent, azido-dPEG®4-OH can participate in CuAAC, RuAAC, and SPAAC reactions. Because Vector Laboratories’ dPEG® products are amphiphilic, these reactions can occur almost equally well in water or organic solvents. Thus, azido-dPEG®4-OH can be used in conjugations with biomolecules where organic solvents may damage the conjugate target.

The primary alcohol group on the opposite end of the linker can be used as a neutrally charged functional group. In this function, the alcohol enhances the water solubility of the conjugate molecule. Alternatively, the alcohol group can be functionalized with reactive groups and used to modify the conjugate further.

Specifications

Unit Size100mg, 1000mg
Molecular Weight219.24; single compound
Chemical formulaC₈H₁₇N₃O₄
CAS
86770-67-4
Purity> 98%
Spacers
dPEG® Spacer is 14 atoms and 15.3 Å
Shipping
Ambient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post Azido-dPEG®₄-OH appeared first on VectorLabs.

]]> m-dPEG®₂₄-Azide (Azido-m-dPEG®₂₄) https://staging.vectorlabs.com/products/m-dpeg24-azide-azido-m-dpeg24/ Sat, 24 Feb 2024 02:11:28 +0000 https://staging.vectorlabs.com/?post_type=product&p=36378 m-dPEG®24-azide, product number QBD-10540, also known as azido-m-dPEG®24, is a monodispersed PEG product used in click chemistry applications. A non-reactive, charge-neutral methyl group and an alkyne-reactive azido group, respectively, terminate the two ends of the long (74 atoms), single molecular weight, discrete PEG (dPEG®) spacer. Both metal-catalyzed (Cu(I), Ru) azide-alkyne cycloaddition (CuAAC, RuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) work with this product. Possible click chemistry-based applications for this product include the construction of dendrimers and hydrogels and the modification of alkyne-functionalized surfaces or biomolecules containing alkyne groups.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 1114.32; single compound
Chemical formula C₄₉H₉₉N₃O₂₄
CAS 89485-61-0
Purity > 97%
Spacers dPEG® Spacer is 74 atoms and 86.9 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₂₄-Azide (Azido-m-dPEG®₂₄) appeared first on VectorLabs.

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Description

m-dPEG®24-azide, product number QBD-10540, also known as azido-m-dPEG®24, is a monodispersed PEG product used in click chemistry applications. A non-reactive, charge-neutral methyl group and an alkyne-reactive azido group, respectively, terminate the two ends of the long (74 atoms), single molecular weight, discrete PEG (dPEG®) spacer. Both metal-catalyzed (Cu(I), Ru) azide-alkyne cycloaddition (CuAAC, RuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) work with this product. Possible click chemistry-based applications for this product include the construction of dendrimers and hydrogels and the modification of alkyne-functionalized surfaces or biomolecules containing alkyne groups.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight1114.32; single compound
Chemical formulaC₄₉H₉₉N₃O₂₄
CAS89485-61-0
Purity> 97%
SpacersdPEG® Spacer is 74 atoms and 86.9 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post m-dPEG®₂₄-Azide (Azido-m-dPEG®₂₄) appeared first on VectorLabs.

]]> m-dPEG®₁₂-Azide (Azido-m-dPEG®₁₂) https://staging.vectorlabs.com/products/m-dpeg12-azide-azido-m-dpeg12/ Sat, 24 Feb 2024 02:11:26 +0000 https://staging.vectorlabs.com/?post_type=product&p=36362 m-dPEG®12-azide, product number 10536, also known as azido-m-dPEG®12, is a monodispersed PEG product used in click chemistry applications. A non-reactive, charge-neutral methyl group and an alkyne-reactive azido group, respectively, terminate the two ends of the medium-length (38 atoms), single molecular weight, discrete PEG (dPEG®) spacer. Both metal-catalyzed (Cu(I), Ru) azide-alkyne cycloaddition (CuAAC, RuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) work with this product. Possible click chemistry-based applications for this product include the construction of dendrimers and hydrogels and the modification of alkyne-functionalized surfaces or biomolecules containing alkyne groups.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 585.69; single compound
Chemical formula C₂₅H₅₁N₃O₁₂
CAS 89485-61-0
Purity > 98%
Spacers dPEG® Spacer is 38 atoms and 44.0 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₁₂-Azide (Azido-m-dPEG®₁₂) appeared first on VectorLabs.

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Description

m-dPEG®12-azide, product number QBD-10536, also known as azido-m-dPEG®12, is a monodispersed PEG product used in click chemistry applications. A non-reactive, charge-neutral methyl group and an alkyne-reactive azido group, respectively, terminate the two ends of the medium-length (38 atoms), single molecular weight, discrete PEG (dPEG®) spacer. Both metal-catalyzed (Cu(I), Ru) azide-alkyne cycloaddition (CuAAC, RuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) work with this product. Possible click chemistry-based applications for this product include the construction of dendrimers and hydrogels and the modification of alkyne-functionalized surfaces or biomolecules containing alkyne groups.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight585.69; single compound
Chemical formulaC₂₅H₅₁N₃O₁₂
CAS89485-61-0
Purity> 98%
SpacersdPEG® Spacer is 38 atoms and 44.0 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post m-dPEG®₁₂-Azide (Azido-m-dPEG®₁₂) appeared first on VectorLabs.

]]> m-dPEG®₈-Azide (Azido-m-dPEG®₈) https://staging.vectorlabs.com/products/m-dpeg8-azide-azido-m-dpeg8/ Sat, 24 Feb 2024 02:11:25 +0000 https://staging.vectorlabs.com/?post_type=product&p=36353 m-dPEG®8-azide, product number 10534, also known as azido-m-dPEG®8, is a monodispersed PEG product used in click chemistry applications. A non-reactive, charge-neutral methyl group and an alkyne-reactive azido group, respectively, terminate the two ends of the medium-length (26 atoms), single molecular weight, discrete PEG (dPEG®) spacer. Both metal-catalyzed (Cu(I), Ru) azide-alkyne cycloaddition (CuAAC, RuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) work with this product. Possible click chemistry-based applications for this product include the construction of dendrimers and hydrogels and the modification of alkyne-functionalized surfaces or biomolecules containing alkyne groups.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 409.48; single compound
Chemical formula C₁₇H₃₅N₃O₈
CAS 869718-80-9
Purity > 98%
Spacers dPEG® Spacer is 26 atoms and 29.7 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₈-Azide (Azido-m-dPEG®₈) appeared first on VectorLabs.

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Description

m-dPEG®8-azide, product number QBD-10534, also known as azido-m-dPEG®8, is a monodispersed PEG product used in click chemistry applications. A non-reactive, charge-neutral methyl group and an alkyne-reactive azido group, respectively, terminate the two ends of the medium-length (26 atoms), single molecular weight, discrete PEG (dPEG®) spacer. Both metal-catalyzed (Cu(I), Ru) azide-alkyne cycloaddition (CuAAC, RuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) work with this product. Possible click chemistry-based applications for this product include the construction of dendrimers and hydrogels and the modification of alkyne-functionalized surfaces or biomolecules containing alkyne groups.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight409.48; single compound
Chemical formulaC₁₇H₃₅N₃O₈
CAS869718-80-9
Purity> 98%
SpacersdPEG® Spacer is 26 atoms and 29.7 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Clickable Poly(ethylene glycol)-Microsphere-Based Cell Scaffolds. Peter K. Nguyen, Christopher G Snyder, Jason D. Shields, Amanda W. Smith, Donald L. Elbert. Macromolecular Journals. 2013, 214 (8) 948-956. March 4, 2013. DOI: 10.1002/macp.201300023.

The post m-dPEG®₈-Azide (Azido-m-dPEG®₈) appeared first on VectorLabs.

]]> m-dPEG®₄-Azide (Azido-m-dPEG®₄) https://staging.vectorlabs.com/products/m-dpeg4-azide-azido-m-dpeg4/ Sat, 24 Feb 2024 02:11:24 +0000 https://staging.vectorlabs.com/?post_type=product&p=36345 m-dPEG®4-azide, product number 10532, also known as azido-m-dPEG®4, is a monodispersed PEG product used in click chemistry applications. A non-reactive, charge-neutral methyl group and an alkyne-reactive azido group, respectively, terminate the two ends of the short (14 atoms), single molecular weight, discrete PEG (dPEG®) spacer. Both metal-catalyzed (Cu(I), Ru) azide-alkyne cycloaddition (CuAAC, RuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) work with this product. Possible click chemistry-based applications for this product include the construction of dendrimers and hydrogels and the modification of alkyne-functionalized surfaces or biomolecules containing alkyne groups.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 233.26; single compound
Chemical formula C₉H₁₉N₃O₄
CAS 606130-90-9
Purity > 98%
Spacers dPEG® Spacer is 14 atoms and 15.5 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₄-Azide (Azido-m-dPEG®₄) appeared first on VectorLabs.

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Description

m-dPEG®4-azide, product number QBD-10532, also known as azido-m-dPEG®4, is a monodispersed PEG product used in click chemistry applications. A non-reactive, charge-neutral methyl group and an alkyne-reactive azido group, respectively, terminate the two ends of the short (14 atoms), single molecular weight, discrete PEG (dPEG®) spacer. Both metal-catalyzed (Cu(I), Ru) azide-alkyne cycloaddition (CuAAC, RuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) work with this product. Possible click chemistry-based applications for this product include the construction of dendrimers and hydrogels and the modification of alkyne-functionalized surfaces or biomolecules containing alkyne groups.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight233.26; single compound
Chemical formulaC₉H₁₉N₃O₄
CAS606130-90-9
Purity> 98%
SpacersdPEG® Spacer is 14 atoms and 15.5 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Clickable Poly(ethylene glycol)-Microsphere-Based Cell Scaffolds. Peter K. Nguyen, Christopher G Snyder, Jason D. Shields, Amanda W. Smith, Donald L. Elbert. Macromolecular Journals. 2013, 214 (8) 948-956. March 4, 2013. DOI: 10.1002/macp.201300023.

The post m-dPEG®₄-Azide (Azido-m-dPEG®₄) appeared first on VectorLabs.

]]> m-dPEG®₃₆-Azide (Azido-m-dPEG®₃₆) https://staging.vectorlabs.com/products/m-dpeg36-azide-azido-m-dpeg36/ Sat, 24 Feb 2024 02:11:23 +0000 https://staging.vectorlabs.com/?post_type=product&p=36337 m-dPEG®36-azide, product number QBD-10531, also known as azido-m-dPEG®36, is a monodispersed PEG product used in click chemistry applications. A non-reactive, charge-neutral methyl group and an alkyne-reactive azido group, respectively, terminate the two ends of the long (110 atoms), single molecular weight, discrete PEG (dPEG®) spacer. Both metal-catalyzed (Cu(I), Ru) azide-alkyne cycloaddition (CuAAC, RuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) work with this product. Possible click chemistry-based applications for this product include the construction of dendrimers and hydrogels and the modification of alkyne-functionalized surfaces or biomolecules containing alkyne groups.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 1642.95; single compound
Chemical formula C₇₃H₁₄₇N₃O₃₆
CAS 89485-61-0
Purity > 95%
Spacers dPEG® Spacer is 110 atoms and 131.2 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₃₆-Azide (Azido-m-dPEG®₃₆) appeared first on VectorLabs.

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Description

m-dPEG®36-azide, product number QBD-10531, also known as azido-m-dPEG®36, is a monodispersed PEG product used in click chemistry applications. A non-reactive, charge-neutral methyl group and an alkyne-reactive azido group, respectively, terminate the two ends of the long (110 atoms), single molecular weight, discrete PEG (dPEG®) spacer. Both metal-catalyzed (Cu(I), Ru) azide-alkyne cycloaddition (CuAAC, RuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC) work with this product. Possible click chemistry-based applications for this product include the construction of dendrimers and hydrogels and the modification of alkyne-functionalized surfaces or biomolecules containing alkyne groups.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight1642.95; single compound
Chemical formulaC₇₃H₁₄₇N₃O₃₆
CAS89485-61-0
Purity> 95%
SpacersdPEG® Spacer is 110 atoms and 131.2 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post m-dPEG®₃₆-Azide (Azido-m-dPEG®₃₆) appeared first on VectorLabs.

]]> Azido-dPEG®₂₄-acid https://staging.vectorlabs.com/products/azido-dpeg24-acid/ Sat, 24 Feb 2024 02:11:14 +0000 https://staging.vectorlabs.com/?post_type=product&p=36289 Azido-dPEG®24-acid, product number QBD-10514, is a click chemistry reagent consisting of an azide and a propionic acid group on opposite ends of a long (76 atoms), hydrophilic, single molecular weight polyethylene glycol spacer with a discrete chain length (dPEG®). The azide moiety acts as an alkyne partner for metal-catalyzed (i.e., Cu(I), Ru) or strain-promoted click chemistry, or as a masked amine. The propanoic acid moiety can be coupled to a primary or secondary amine through an acylation reaction.

Our dPEG® products are single molecular weight compounds. Unlike traditional, polymeric polyethylene glycol (PEG), dPEG® products contain a single molecular weight PEG chain with a discrete chain length. The use of dPEG® instead of traditional polymer PEG allows accurate characterization of conjugates without sacrificing any of the benefits of PEG.

Activation of the propionic acid moiety with an acylating agent enables conjugation of azido-dPEG®24-acid to a primary or secondary amine. Popular acylating agents include such as N-hydroxysuccinimide (NHS); 2,3,5,6-tetrafluorophenol (TFP); or 2,3,4,5,6-pentafluorophenol (PFP). Alternatively, 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) or another suitable carbodiimide can be used to couple the acid moiety directly to an amine without prior activation.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 1172.35; single compound
Chemical formula C₅₁H₁₀₁N₃O₂₆
CAS 1167575-20-3
Purity > 97%
Spacers dPEG® Spacer is 76 atoms and 90.4 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post Azido-dPEG®₂₄-acid appeared first on VectorLabs.

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Description

Azido-dPEG®24-acid, product number QBD-10514, is a click chemistry reagent consisting of an azide and a propionic acid group on opposite ends of a long (76 atoms), hydrophilic, single molecular weight polyethylene glycol spacer with a discrete chain length (dPEG®). The azide moiety acts as an alkyne partner for metal-catalyzed (i.e., Cu(I), Ru) or strain-promoted click chemistry, or as a masked amine. The propanoic acid moiety can be coupled to a primary or secondary amine through an acylation reaction.

Our dPEG® products are single molecular weight compounds. Unlike traditional, polymeric polyethylene glycol (PEG), dPEG® products contain a single molecular weight PEG chain with a discrete chain length. The use of dPEG® instead of traditional polymer PEG allows accurate characterization of conjugates without sacrificing any of the benefits of PEG.

Activation of the propionic acid moiety with an acylating agent enables conjugation of azido-dPEG®24-acid to a primary or secondary amine. Popular acylating agents include such as N-hydroxysuccinimide (NHS); 2,3,5,6-tetrafluorophenol (TFP); or 2,3,4,5,6-pentafluorophenol (PFP). Alternatively, 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) or another suitable carbodiimide can be used to couple the acid moiety directly to an amine without prior activation.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight1172.35; single compound
Chemical formulaC₅₁H₁₀₁N₃O₂₆
CAS1167575-20-3
Purity> 97%
SpacersdPEG® Spacer is 76 atoms and 90.4 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post Azido-dPEG®₂₄-acid appeared first on VectorLabs.

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