Alkyne – VectorLabs https://staging.vectorlabs.com From linker design and synthesis, bioconjugated design and manufacturing, biomolecule labeling and functionalization, and detection system and solutions, our team is here to help you move forward, with impact. Wed, 22 Oct 2025 17:10:53 +0000 en-US hourly 1 https://wordpress.org/?v=6.9 https://staging.vectorlabs.com/wp-content/uploads/2024/11/V-favicon-02-100x100.png Alkyne – VectorLabs https://staging.vectorlabs.com 32 32 Alkynyl Stearic Acid https://staging.vectorlabs.com/products/alkynyl-stearic-acid/ Tue, 19 Sep 2023 19:16:42 +0000 https://staging.vectorlabs.com/?post_type=product&p=21778 Description

Alkynyl stearic acid is can be used to identify and characterize the post-translational acylation of proteins using the powerful click chemistry, a simple and robust two-step labeling and detection technique. Due to the very small size of the alkyne group and its complete absence in any natural molecules the presence of alkynyl group does not affect the biodistribution of alkynyl palmitic acid in comparison to the natural palmitic acid making it a suitable substrate for enzymes.

Specifications

Unit Size 5 mg, 25 mg, 100 mg
Molecular weight 280.45
Chemical composition C18H32O2
CAS 34450-18-5
Solubility DMSO, DMF, DCM, THF, Chloroform
Purity >95% (H NMR)
Appearance White crystalline
Storage Conditions -20°C.
Shipping Conditions Ambient temperature

The post Alkynyl Stearic Acid appeared first on VectorLabs.

]]>

Description

Alkynyl stearic acid is can be used to identify and characterize the post-translational acylation of proteins using the powerful click chemistry, a simple and robust two-step labeling and detection technique. Due to the very small size of the alkyne group and its complete absence in any natural molecules the presence of alkynyl group does not affect the biodistribution of alkynyl palmitic acid in comparison to the natural palmitic acid making it a suitable substrate for enzymes.

Specifications

Unit Size5 mg, 25 mg, 100 mg
Molecular weight280.45
Chemical compositionC18H32O2
CAS34450-18-5
SolubilityDMSO, DMF, DCM, THF, Chloroform
Purity>95% (H NMR)
AppearanceWhite crystalline
Storage Conditions-20°C.
Shipping ConditionsAmbient temperature

Documents

The post Alkynyl Stearic Acid appeared first on VectorLabs.

]]> Alkynyl Palmitic Acid https://staging.vectorlabs.com/products/alkynyl-palmitic-acid/ Tue, 19 Sep 2023 19:16:41 +0000 https://staging.vectorlabs.com/?post_type=product&p=21774 Description

Alkynyl myristic acid is can be used to identify and characterize the post-translational myristylated proteins Alkynyl palmitic acid (15-hexadecynoic acid or Palmitic acid (15-yne)) is a modified palmitic acid with an ω-terminal alkyne. Alkynyl palmitic acid often used to identify and characterize the post-translational S-palmitoylation of proteins using the powerful click chemistry (see References).

Specifications

Unit Size 5 mg, 25 mg, 100 mg
Alternative name 15-hexadecynoic acid, Palmitic acid (15-yne)
Molecular weight 252.39
Chemical composition C16H28O2
CAS 99208-90-9
Solubility DMSO, DMF, DCM, THF, Chloroform
Purity >95% (H NMR)
Appearance White crystalline
Storage Conditions -20°C.
Shipping Conditions Ambient temperature

The post Alkynyl Palmitic Acid appeared first on VectorLabs.

]]>

Description

Alkynyl myristic acid is can be used to identify and characterize the post-translational myristylated proteins Alkynyl palmitic acid (15-hexadecynoic acid or Palmitic acid (15-yne)) is a modified palmitic acid with an ω-terminal alkyne. Alkynyl palmitic acid often used to identify and characterize the post-translational S-palmitoylation of proteins using the powerful click chemistry (see References).

Specifications

Unit Size5 mg, 25 mg, 100 mg
Alternative name15-hexadecynoic acid, Palmitic acid (15-yne)
Molecular weight252.39
Chemical compositionC16H28O2
CAS99208-90-9
SolubilityDMSO, DMF, DCM, THF, Chloroform
Purity>95% (H NMR)
AppearanceWhite crystalline
Storage Conditions-20°C.
Shipping ConditionsAmbient temperature

Documents

Selected References

  1. Gray, R. A. V., et al. (2021). Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry. JoVE Journal, 10 (3791), 62107. [JoVE Journal]
  2. Li, B., et al. (2020). TMEM132A, a Novel Wnt Signaling Pathway Regulator Through Wntless (WLS) Interaction. Front Cell Dev Biol., 8, 599890. [PubMed]
  3. Lee, M.T., et al. (2020). Dietary sphinganine is selectively assimilated by members of themammaliangut microbiome. J Lipid Res . [PubMed]
  4. White, F. K. H., et al. (2019). S-Palmitoylation of junctophilin-2 is critical for its role in tethering the sarcoplasmic reticulum to the plasma membrane. J Biol Chem., 294 (36), 13487-13501. [PubMed]

The post Alkynyl Palmitic Acid appeared first on VectorLabs.

]]> Alkynyl Myristic Acid https://staging.vectorlabs.com/products/alkynyl-myristic-acid/ Tue, 19 Sep 2023 19:16:18 +0000 https://staging.vectorlabs.com/?post_type=product&p=21768 Description

Alkynyl myristic acid is can be used to identify and characterize the post-translational myristylated proteins using a simple and robust two-step labeling and detection technique. Due to the very small size of the alkyne group and its complete absence in any natural molecules the presence of the alkyne group does not affect the biodistribution of alkynyl myristic acid in comparison to the natural palmitic acid making it a suitable substrate for enzymes.

Specifications

Unit Size 5 mg, 25 mg, 100 mg
Molecular weight 244.32
Chemical composition C14H24O2
CAS 82909-47-5
Solubility DMSO, DMF, DCM, THF, Chloroform
Purity >95% (H NMR)
Appearance White crystalline
Storage Conditions -20°C.
Shipping Conditions Ambient temperature

The post Alkynyl Myristic Acid appeared first on VectorLabs.

]]>

Description

Alkynyl myristic acid is can be used to identify and characterize the post-translational myristylated proteins using a simple and robust two-step labeling and detection technique. Due to the very small size of the alkyne group and its complete absence in any natural molecules the presence of the alkyne group does not affect the biodistribution of alkynyl myristic acid in comparison to the natural palmitic acid making it a suitable substrate for enzymes.

Specifications

Unit Size5 mg, 25 mg, 100 mg
Molecular weight244.32
Chemical compositionC14H24O2
CAS82909-47-5
SolubilityDMSO, DMF, DCM, THF, Chloroform
Purity>95% (H NMR)
AppearanceWhite crystalline
Storage Conditions-20°C.
Shipping ConditionsAmbient temperature

Documents

Selected References

  1. Gray, R. A. V., et al. (2021). Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry. JoVE Journal, 10 (3791), 62107. [JoVE Journal]
 

The post Alkynyl Myristic Acid appeared first on VectorLabs.

]]> Alkyne-PEG4-Acid https://staging.vectorlabs.com/products/alkyne-peg4-acid/ Tue, 19 Sep 2023 17:40:10 +0000 https://staging.vectorlabs.com/?post_type=product&p=21163 Description

Alkyne-PEG4-Acid is a polyethylene glycol-containing reagent with a terminal carboxylic acid (–COOH) that can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) forming a stable amide bond. The terminal alkyne group reacts with azides by a mechanism known as the Cu-catalyzed click reaction enabling efficient and specific conjugation of derivatized molecules in biological samples.

Specifications

Unit Size 100 mg, 1000 mg
Molecular weight 304.34
Chemical composition C14H24O7
CAS 1245823-51-1
Solubility DMSO, DMF, DCM, THF, Chloroform
Purity >95% (HPLC)
Appearance Colorless to slightly yellow oil
Storage Conditions -20°C. Desiccate
Shipping Conditions Ambient temperature

The post Alkyne-PEG4-Acid appeared first on VectorLabs.

]]>

Description

Alkyne-PEG4-Acid is a polyethylene glycol-containing reagent with a terminal carboxylic acid (–COOH) that can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) forming a stable amide bond. The terminal alkyne group reacts with azides by a mechanism known as the Cu-catalyzed click reaction enabling efficient and specific conjugation of derivatized molecules in biological samples.

Specifications

Unit Size100 mg, 1000 mg
Molecular weight304.34
Chemical compositionC14H24O7
CAS1245823-51-1
SolubilityDMSO, DMF, DCM, THF, Chloroform
Purity>95% (HPLC)
AppearanceColorless to slightly yellow oil
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

Documents

Selected References

  1. Graham, A. J., et al. (2022). Extracellular Electron Transfer Enables Cellular Control of Cu(I)-Catalyzed Alkyne-Azide Cycloaddition. ACS Cent Sci., 8 (2), 246-257. [PubMed]

The post Alkyne-PEG4-Acid appeared first on VectorLabs.

]]>