Hydroxy – VectorLabs https://staging.vectorlabs.com From linker design and synthesis, bioconjugated design and manufacturing, biomolecule labeling and functionalization, and detection system and solutions, our team is here to help you move forward, with impact. Wed, 22 Oct 2025 17:18:52 +0000 en-US hourly 1 https://wordpress.org/?v=6.9 https://staging.vectorlabs.com/wp-content/uploads/2024/11/V-favicon-02-100x100.png Hydroxy – VectorLabs https://staging.vectorlabs.com 32 32 Hydroxy-dPEG®₂₄-t-butyl ester https://staging.vectorlabs.com/products/hydroxy-dpeg24-t-butyl-ester/ Sat, 24 Feb 2024 02:12:04 +0000 https://staging.vectorlabs.com/?post_type=product&p=36704 Hydroxy-dPEG®24-t-butyl ester, product number QBD-10722, is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. Alternatively, the hydroxy group can react with isothiocyanates or active esters of carboxylic acids to form new conjugates. The tert-butyl ester deprotects with trifluoroacetic acid (TFA) or formic acid, exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 1203.45; single compound
Chemical formula C₅₅H₁₁₀O₂₇
CAS 1186025-29-5
Purity > 98%
Spacers dPEG® Spacer is 86 atoms and 88.5 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetontrile, DMAC or DMSO.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post Hydroxy-dPEG®₂₄-t-butyl ester appeared first on VectorLabs.

]]>

Description

Hydroxy-dPEG®24-t-butyl ester, product number QBD-10722, is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. Alternatively, the hydroxy group can react with isothiocyanates or active esters of carboxylic acids to form new conjugates. The tert-butyl ester deprotects with trifluoroacetic acid (TFA) or formic acid, exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Specifications

Unit Size100mg, 1000mg
Molecular Weight1203.45; single compound
Chemical formulaC₅₅H₁₁₀O₂₇
CAS1186025-29-5
Purity> 98%
SpacersdPEG® Spacer is 86 atoms and 88.5 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetontrile, DMAC or DMSO.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post Hydroxy-dPEG®₂₄-t-butyl ester appeared first on VectorLabs.

]]> Hydroxy-dPEG®₁₂-t-butyl ester https://staging.vectorlabs.com/products/hydroxy-dpeg12-t-butyl-ester/ Sat, 24 Feb 2024 02:12:02 +0000 https://staging.vectorlabs.com/?post_type=product&p=36696 Hydroxy-dPEG®12-t-butyl ester, product number QBD-10719, is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. Alternatively, the hydroxy group can react with isothiocyanates or active esters of carboxylic acids to form new conjugates. The tert-butyl ester deprotects with trifluoroacetic acid (TFA) or formic acid, exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 674.81; single compound
Chemical formula C₃₁H₆₂O₁₅
CAS 1186025-29-5
Purity > 98%
Spacers dPEG® Spacer is 40 atoms and 46.4 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetontrile, DMAC or DMSO.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post Hydroxy-dPEG®₁₂-t-butyl ester appeared first on VectorLabs.

]]>

Description

Hydroxy-dPEG®12-t-butyl ester, product number QBD-10719, is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. Alternatively, the hydroxy group can react with isothiocyanates or active esters of carboxylic acids to form new conjugates. The tert-butyl ester deprotects with trifluoroacetic acid (TFA) or formic acid, exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Specifications

Unit Size100mg, 1000mg
Molecular Weight674.81; single compound
Chemical formulaC₃₁H₆₂O₁₅
CAS1186025-29-5
Purity> 98%
SpacersdPEG® Spacer is 40 atoms and 46.4 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetontrile, DMAC or DMSO.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post Hydroxy-dPEG®₁₂-t-butyl ester appeared first on VectorLabs.

]]> Hydroxy-dPEG®₆-t-butyl ester https://staging.vectorlabs.com/products/hydroxy-dpeg6-t-butyl-ester/ Sat, 24 Feb 2024 02:12:01 +0000 https://staging.vectorlabs.com/?post_type=product&p=36666 Hydroxy-dPEG®6-t-butyl ester, product number QBD-10717, is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. Alternatively, the hydroxy group can react with isothiocyanates or active esters of carboxylic acids to form new conjugates. The tert-butyl ester deprotects with trifluoroacetic acid (TFA) or formic acid, exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 410.50; single compound
Chemical formula C₁₉H₃₈O₉
CAS N/A
Purity > 98%
Spacers dPEG® Spacer is 22 atoms and 25.1 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetontrile, DMAC or DMSO.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post Hydroxy-dPEG®₆-t-butyl ester appeared first on VectorLabs.

]]>

Description

Hydroxy-dPEG®6-t-butyl ester, product number QBD-10717, is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. Alternatively, the hydroxy group can react with isothiocyanates or active esters of carboxylic acids to form new conjugates. The tert-butyl ester deprotects with trifluoroacetic acid (TFA) or formic acid, exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Specifications

Unit Size100mg, 1000mg
Molecular Weight410.50; single compound
Chemical formulaC₁₉H₃₈O₉
CASN/A
Purity> 98%
SpacersdPEG® Spacer is 22 atoms and 25.1 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetontrile, DMAC or DMSO.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post Hydroxy-dPEG®₆-t-butyl ester appeared first on VectorLabs.

]]> dPEG®₁₂-diol https://staging.vectorlabs.com/products/dpeg12-diol/ Sat, 24 Feb 2024 02:07:42 +0000 https://staging.vectorlabs.com/?post_type=product&p=35636 dPEG®12-diol, product number QBD-10261, is a homobifunctional, monodispersed (single molecular weight and chain length) PEG diol that is useful for creating new PEG products. Both ends terminate with hydroxy groups. The primary use of this product is as a building block for other products. An unlimited number of functional or protecting groups can modify the termini of dPEG®12-diol. Moreover, dPEG®12-diol can function as a crosslinker by reacting the terminal alcohols with active carboxylic acid esters or isothiocyanates. Conjugates containing PEG have increased hydrodynamic volume and hydrophilicity.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 546.65; single compound
Chemical formula C₂₄H₅₀O₁₃
CAS 25322-68-3
Purity > 98%
Spacers dPEG® Spacer is 37 atoms and 42.8 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetontrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post dPEG®₁₂-diol appeared first on VectorLabs.

]]>

Description

dPEG®12-diol, product number QBD-10261, is a homobifunctional, monodispersed (single molecular weight and chain length) PEG diol that is useful for creating new PEG products. Both ends terminate with hydroxy groups. The primary use of this product is as a building block for other products. An unlimited number of functional or protecting groups can modify the termini of dPEG®12-diol. Moreover, dPEG®12-diol can function as a crosslinker by reacting the terminal alcohols with active carboxylic acid esters or isothiocyanates. Conjugates containing PEG have increased hydrodynamic volume and hydrophilicity.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight546.65; single compound
Chemical formulaC₂₄H₅₀O₁₃
CAS25322-68-3
Purity> 98%
SpacersdPEG® Spacer is 37 atoms and 42.8 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetontrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post dPEG®₁₂-diol appeared first on VectorLabs.

]]> Hydroxy-dPEG®₄-t-butyl ester https://staging.vectorlabs.com/products/hydroxy-dpeg4-t-butyl-ester/ Sat, 24 Feb 2024 02:07:20 +0000 https://staging.vectorlabs.com/?post_type=product&p=35481 Hydroxy-dPEG®4-t-butyl ester, product number QBD-10223, is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. The tert-butyl ester deprotects with trifluoroacetic acid (TFA), exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 332.39; single compound
Chemical formula C₁₅H₃₀O₇
CAS 518044-32-1
Purity > 98%
Spacers dPEG® Spacer is 16 atoms and 18.0 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetontrile, DMAC or DMSO.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post Hydroxy-dPEG®₄-t-butyl ester appeared first on VectorLabs.

]]>

Description

Hydroxy-dPEG®4-t-butyl ester, product number QBD-10223, is a versatile building block based upon a monodispersed polyethylene glycol (PEG) chain. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules. The tert-butyl ester deprotects with trifluoroacetic acid (TFA), exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight332.39; single compound
Chemical formulaC₁₅H₃₀O₇
CAS518044-32-1
Purity> 98%
SpacersdPEG® Spacer is 16 atoms and 18.0 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetontrile, DMAC or DMSO.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

Documents

References

  1. Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post Hydroxy-dPEG®₄-t-butyl ester appeared first on VectorLabs.

]]> Hydroxy-dPEG®₈-t-butyl ester https://staging.vectorlabs.com/products/hydroxy-dpeg8-t-butyl-ester/ Sat, 24 Feb 2024 02:05:15 +0000 https://staging.vectorlabs.com/?post_type=product&p=35235 Hydroxy-dPEG®8-t-butyl ester, product number QBD-10185, is a versatile discrete PEG building block based upon a monodispersed polyethylene glycol (PEG) chain. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules.

Alternatively, the hydroxy group can react with isothiocyanates or active esters of carboxylic acids to form new conjugates. The tert-butyl ester deprotects with trifluoroacetic acid (TFA) or formic acid, exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 498.60; single compound
Chemical formula C₂₃H₄₆O₁₁
CAS 1334177-84-2
Purity > 98%
Spacers dPEG® Spacer is 28 atoms and 32.1 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetontrile, DMAC or DMSO.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post Hydroxy-dPEG®₈-t-butyl ester appeared first on VectorLabs.

]]>

Description

Hydroxy-dPEG®8-t-butyl ester, product number QBD-10185, is a versatile discrete PEG building block based upon a monodispersed polyethylene glycol (PEG) chain. A primary alcohol group terminates one end of the molecule. The opposite end is a propionic acid group protected as the tert-butyl ester. The terminal hydroxy group can be functionalized with various reactive groups to permit direct modification of surfaces, small molecules, or biomolecules.

Alternatively, the hydroxy group can react with isothiocyanates or active esters of carboxylic acids to form new conjugates. The tert-butyl ester deprotects with trifluoroacetic acid (TFA) or formic acid, exposing the terminal propionic acid, which can then be activated as the NHS or TFP ester or directly coupled to an amine using a suitable carbodiimide.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight498.60; single compound
Chemical formulaC₂₃H₄₆O₁₁
CAS1334177-84-2
Purity> 98%
SpacersdPEG® Spacer is 28 atoms and 32.1 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetontrile, DMAC or DMSO.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

Documents

References

  1. Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.
  2. How a grafting anchor tailors cellular uptake and in vivo fate of dendronized iron oxide nanoparticles. C. Bordeianu, A. Parat, C. Affolter-Zbaraszczuk, R. N. Muller, S. Boutry, S. Begin-Colin, F. Meyer, S. Laurent, and D. Felder-Flesch. Journal of Materials Chemistry B. 2017, 2013 (00) pp 1-3. May 26, 2017. DOI: 10.1039/C7TB00781G.

The post Hydroxy-dPEG®₈-t-butyl ester appeared first on VectorLabs.

]]>