Ac4GalNR – VectorLabs https://staging.vectorlabs.com From linker design and synthesis, bioconjugated design and manufacturing, biomolecule labeling and functionalization, and detection system and solutions, our team is here to help you move forward, with impact. Wed, 22 Oct 2025 17:05:25 +0000 en-US hourly 1 https://wordpress.org/?v=6.9 https://staging.vectorlabs.com/wp-content/uploads/2024/11/V-favicon-02-100x100.png Ac4GalNR – VectorLabs https://staging.vectorlabs.com 32 32 N-(4-pentynoyl)-galactosamine tetraacylated (Ac4GalNAl) https://staging.vectorlabs.com/products/n-4-pentynoyl-galactosamine-tetraacylated-ac4galnal/ Tue, 19 Sep 2023 19:19:19 +0000 https://staging.vectorlabs.com/?post_type=product&p=21821 Description

Ac4GalNAl is an unnatural alkyne-containing monosaccharide building block. The alkyne moiety can be used for modification though chemoselective ligation chemistries including CuAAC or various Pd-catalyzed coupling reactions. The acetyl groups increase solubility in many solvents and make handling of this building easier.

Specifications

Unit Size 5 mg, 25 mg, 100 mg
Molecular weight 427.40
Chemical composition C19H25NO10
CAS 1658458-26-4
Solubility DMSO, DMF, DCM, THF, Chloroform
Purity >90%
Appearance White to grey amorphous solid
Storage Conditions -20°C.
Shipping Conditions Ambient temperature

The post N-(4-pentynoyl)-galactosamine tetraacylated (Ac4GalNAl) appeared first on VectorLabs.

]]>

Description

Ac4GalNAl is an unnatural alkyne-containing monosaccharide building block. The alkyne moiety can be used for modification though chemoselective ligation chemistries including CuAAC or various Pd-catalyzed coupling reactions. The acetyl groups increase solubility in many solvents and make handling of this building easier.

Specifications

Unit Size5 mg, 25 mg, 100 mg
Molecular weight427.40
Chemical compositionC19H25NO10
CAS1658458-26-4
SolubilityDMSO, DMF, DCM, THF, Chloroform
Purity>90%
AppearanceWhite to grey amorphous solid
Storage Conditions-20°C.
Shipping ConditionsAmbient temperature

Documents

Selected References

  1. Wood, T. M., et al. (2021). Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase. ACS Chem. Biol., [PubMed]
  2. Daughtry, J. L., et al. (2020). Clickable Galactose Analogues for Imaging Glycans in Developing Zebrafish. ACS Chem Biol., 15 (2), 318-324. [PubMed]
 

The post N-(4-pentynoyl)-galactosamine tetraacylated (Ac4GalNAl) appeared first on VectorLabs.

]]> N-azidoacetylgalactosamine-tetraacylated (Ac4GalNAz) https://staging.vectorlabs.com/products/n-azidoacetylgalactosamine-tetraacylated-ac4galnaz/ Tue, 19 Sep 2023 19:18:00 +0000 https://staging.vectorlabs.com/?post_type=product&p=21800 Description

The unnatural azido-containing monosaccharide building block. The azide moiety can be used for modification though chemoselective ligation chemistries including CuAAC, Cu-free click reaction or Staudinger ligation. The acetyl groups increase solubility in many solvents and make handling of this reagent easier.

Specifications

Unit Size 5 mg, 25 mg, 100 mg
Molecular weight 430.37
Chemical composition C16H22N4O10
CAS 653600-56-7
Solubility DMSO, DMF, DCM, THF, Chloroform
Purity >90%
Appearance White to grey amorphous solid
Storage Conditions -20°C.
Shipping Conditions Ambient temperature

The post N-azidoacetylgalactosamine-tetraacylated (Ac4GalNAz) appeared first on VectorLabs.

]]>

Description

The unnatural azido-containing monosaccharide building block. The azide moiety can be used for modification though chemoselective ligation chemistries including CuAAC, Cu-free click reaction or Staudinger ligation. The acetyl groups increase solubility in many solvents and make handling of this reagent easier.

Specifications

Unit Size5 mg, 25 mg, 100 mg
Molecular weight430.37
Chemical compositionC16H22N4O10
CAS653600-56-7
SolubilityDMSO, DMF, DCM, THF, Chloroform
Purity>90%
AppearanceWhite to grey amorphous solid
Storage Conditions-20°C.
Shipping ConditionsAmbient temperature

Documents

Selected References

  1. Simon P. Wisnovsky, et al. (2020). Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation. PNAS, 117 (41), 25293-25301. [PNAS]
  2. Ranzinger, R., et al. (2020). Mass Spectrometric Method for the Unambiguous Profiling of Cellular Dynamic Glycosylation. ACS Chem. Biol., 15, 10, 2692-2701. [ACSPublications]
  3. Suttapitugsakul, S., et al. (2019). Surface Glycoproteomic Analysis Reveals That Both Unique and Differential Expression of Surface Glycoproteins Determine the Cell Type. Anal. Chem., 91(10), 6934–42. [PubMed]
 

The post N-azidoacetylgalactosamine-tetraacylated (Ac4GalNAz) appeared first on VectorLabs.

]]>