1346 – VectorLabs https://staging.vectorlabs.com From linker design and synthesis, bioconjugated design and manufacturing, biomolecule labeling and functionalization, and detection system and solutions, our team is here to help you move forward, with impact. Wed, 22 Oct 2025 17:04:10 +0000 en-US hourly 1 https://wordpress.org/?v=6.9 https://staging.vectorlabs.com/wp-content/uploads/2024/11/V-favicon-02-100x100.png 1346 – VectorLabs https://staging.vectorlabs.com 32 32 Cy5.5 Alkyne https://staging.vectorlabs.com/products/cy5-5-alkyne/ Tue, 19 Sep 2023 19:13:37 +0000 https://staging.vectorlabs.com/?post_type=product&p=21713 Description

The NIR-fluorescent Cy5.5 Alkynee can be reacted with azides (Ne) via a copper-catalyzed click reaction (CuAAC) forming a stable triazole and does not require elevated temperatures.

Cy5.5 Alkyne is a bright and photostable near-IR probe that spectrally similar to Alexa Fluor® 680, DyLight® 680, and IRDye® 680 dye. The Cy5.5 Alkyne is water-soluble, hydrophilic dye often a reagent of choice for assay where minimal non-specific binding and exceptional brightness is required. The fluorescence of Cy5.5 is pH insensitive from pH 4 to pH 10 and produces minimal autofluorescence of biological specimens in this region of the spectrum. Fluorescence of this long-wavelength Cyanine dye is not visible to the human eye but is readily detected by most imaging systems.

Abs/Em Spectra

Specifications

Unit Size 1 mg, 5 mg, 25 mg, 100 mg
Abs/Em Maxima 678/694 nm
Extinction Coefficient
190,000
Spectrally Similar Dyes Alexa Fluor® 680, IRDye® 680RD, DyLight® 680
Molecular weight 940.09
CAS N/A
Solubility Water, DMSO, DMF
Purity >95% (HPLC)
Appearance Blue solid
Storage Conditions -20°C. Desiccate
Shipping Conditions Ambient temperature

The post Cy5.5 Alkyne appeared first on VectorLabs.

]]>

Description

The NIR-fluorescent Cy5.5 Alkynee can be reacted with azides (Ne) via a copper-catalyzed click reaction (CuAAC) forming a stable triazole and does not require elevated temperatures.

Cy5.5 Alkyne is a bright and photostable near-IR probe that spectrally similar to Alexa Fluor® 680, DyLight® 680, and IRDye® 680 dye. The Cy5.5 Alkyne is water-soluble, hydrophilic dye often a reagent of choice for assay where minimal non-specific binding and exceptional brightness is required. The fluorescence of Cy5.5 is pH insensitive from pH 4 to pH 10 and produces minimal autofluorescence of biological specimens in this region of the spectrum. Fluorescence of this long-wavelength Cyanine dye is not visible to the human eye but is readily detected by most imaging systems.

Specifications

Unit Size1 mg, 5 mg, 25 mg, 100 mg
Abs/Em Maxima678/694 nm
Extinction Coefficient
190,000
Spectrally Similar DyesAlexa Fluor® 680, IRDye® 680RD, DyLight® 680
Molecular weight940.09
CASN/A
SolubilityWater, DMSO, DMF
Purity>95% (HPLC)
AppearanceBlue solid
Storage Conditions-20°C. Desiccate
Shipping ConditionsAmbient temperature

Abs/Em Spectra

Cy5.5

Documents

Selected References

  1. Willems, L. I., et al. (2020). Tandem Bioorthogonal Labeling Uncovers Endogenous Cotranslationally O-GlcNAc Modified Nascent Proteins. J Am Chem Soc., 142 (37), 15729-15739. [PubMed]
 

The post Cy5.5 Alkyne appeared first on VectorLabs.

]]>