1260 – VectorLabs https://staging.vectorlabs.com From linker design and synthesis, bioconjugated design and manufacturing, biomolecule labeling and functionalization, and detection system and solutions, our team is here to help you move forward, with impact. Wed, 22 Oct 2025 17:10:24 +0000 en-US hourly 1 https://wordpress.org/?v=6.9 https://staging.vectorlabs.com/wp-content/uploads/2024/11/V-favicon-02-100x100.png 1260 – VectorLabs https://staging.vectorlabs.com 32 32 TAMRA DBCO https://staging.vectorlabs.com/products/tamra-dbco-a131/ Thu, 18 Jan 2024 16:42:25 +0000 https://staging.vectorlabs.com/?post_type=product&p=42353 Description

TAMRA DBCO reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. This copper-free variation of click reaction overcomes a major shortcoming of copper-catalyzed click reaction – the need for copper catalyst. Copper can damage fluorescent proteins, Quantum Dot nanocyrstals, certain enzymes, and photoproteins like RPE. The presence of copper is also problematic in staining the surface of live cells.

In application where the presence of copper is a concern TAMRA DBCO is an ideal alternative to copper requiring fluorescent alkynes.

TAMRA DBCO reagent is not suitable for staining intracellular components of fixed and permeabilized cells due to high backgrounds.

 

[caption id="attachment_24144" align="alignnone" width="1000"] Abs/Em Spectra[/caption]

Specifications

Unit Size 1 mg, 5 mg, 25 mg
Reactivity Alkyne, cyclooctyne
Abs/Em Maxima 559/584 nm
Extinction coefficient 92,000 cm-1M-1
Solubility DMSO, DMF, MeOH
Spectrally similar dyes Alexa Fluor® 546, TAMRA, CF™ 543, MB™ 543
Molecular weight 936.08
Storage Conditions -20°C.
Shipping Conditions Ambient temperature

 

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Description

TAMRA DBCO reacts with azides via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. This copper-free variation of click reaction overcomes a major shortcoming of copper-catalyzed click reaction – the need for copper catalyst. Copper can damage fluorescent proteins, Quantum Dot nanocyrstals, certain enzymes, and photoproteins like RPE. The presence of copper is also problematic in staining the surface of live cells.

In application where the presence of copper is a concern TAMRA DBCO is an ideal alternative to copper requiring fluorescent alkynes.

TAMRA DBCO reagent is not suitable for staining intracellular components of fixed and permeabilized cells due to high backgrounds.

Specifications

Unit Size1 mg, 5 mg, 25 mg
ReactivityAlkyne, cyclooctyne
Abs/Em Maxima559/584 nm
Extinction coefficient92,000 cm-1M-1
SolubilityDMSO, DMF, MeOH
Spectrally similar dyesAlexa Fluor® 546, TAMRA, CF™ 543, MB™ 543
Molecular weight936.08
Storage Conditions-20°C.
Shipping ConditionsAmbient temperature

Abs/Em Spectra

TAMRA

Documents

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