CBZ Protected Amino Acids – VectorLabs https://staging.vectorlabs.com From linker design and synthesis, bioconjugated design and manufacturing, biomolecule labeling and functionalization, and detection system and solutions, our team is here to help you move forward, with impact. Wed, 22 Oct 2025 17:21:10 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.3 https://staging.vectorlabs.com/wp-content/uploads/2024/11/V-favicon-02-100x100.png CBZ Protected Amino Acids – VectorLabs https://staging.vectorlabs.com 32 32 CBZ-amido-dPEG®₂₄-amido-dPEG®₂₄-acid https://staging.vectorlabs.com/products/cbz-amido-dpeg24-amido-dpeg24-acid/ Sat, 24 Feb 2024 02:16:37 +0000 https://staging.vectorlabs.com/?post_type=product&p=39386 CBZ-N-amido-dPEG®24-amido-dPEG®24-acid, product number 11304, is a benzyloxycarbonyl (Cbz) N-protected amino-dPEG®-acid that provides a very long (152 atoms, 178.7 Å), single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis as well as in many other reactions. Removal of the Cbz protecting group often is orthogonal to the removal of other protecting groups. The carboxylic acid end of the dPEG® linker can be conjugated to free amines, such as the side chain of lysines, using a carbodiimide like EDC, or by activation with an acylating agent like NHS or TFP.

The Cbz protecting group (also called the Z protecting group) is one of the most popular protecting groups for amines. It is stable to base and mildly acidic conditions. It can be cleaved by a variety of methods. The most popular cleavage technique is hydrogenolysis using palladium black or palladium on carbon.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 2408.85; single compound
Chemical formula C₁₁₀H₂₁₀N₂O₅₃
CAS N/A
Purity > 97%
Spacers dPEG® Spacer is 152 atoms and 178.7 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene Chloride, DMSO, DMAC, DMF, Methanol, Acetonitrile or Chloroform.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post CBZ-amido-dPEG®₂₄-amido-dPEG®₂₄-acid appeared first on VectorLabs.

]]>

Description

CBZ-N-amido-dPEG®24-amido-dPEG®24-acid, product number QBD-11304, is a benzyloxycarbonyl (Cbz) N-protected amino-dPEG®-acid that provides a very long (152 atoms, 178.7 Å), single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis as well as in many other reactions. Removal of the Cbz protecting group often is orthogonal to the removal of other protecting groups. The carboxylic acid end of the dPEG® linker can be conjugated to free amines, such as the side chain of lysines, using a carbodiimide like EDC, or by activation with an acylating agent like NHS or TFP.

The Cbz protecting group (also called the Z protecting group) is one of the most popular protecting groups for amines. It is stable to base and mildly acidic conditions. It can be cleaved by a variety of methods. The most popular cleavage technique is hydrogenolysis using palladium black or palladium on carbon.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight2408.85; single compound
Chemical formulaC₁₁₀H₂₁₀N₂O₅₃
CASN/A
Purity> 97%
SpacersdPEG® Spacer is 152 atoms and 178.7 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene Chloride, DMSO, DMAC, DMF, Methanol, Acetonitrile or Chloroform.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post CBZ-amido-dPEG®₂₄-amido-dPEG®₂₄-acid appeared first on VectorLabs.

]]> CBZ-N-amido-dPEG®₃₆-acid https://staging.vectorlabs.com/products/cbz-n-amido-dpeg36-acid/ Sat, 24 Feb 2024 02:13:42 +0000 https://staging.vectorlabs.com/?post_type=product&p=37130 CBZ-N-amido-dPEG®36-acid, product number QBD-10906, is a benzyl carbamate (Cbz) N-protected amino-dPEG®-acid that provides a long (111 atoms, 132.7 Å), single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis to modify the side chain of lysine and in other forms of supramolecular construction. The Cbz protecting group is stable to acidic and basic conditions and is most easily removed using palladium black or palladium on carbon with hydrogen. This makes Cbz removal orthogonal to most other peptide synthesis deprotection reactions.

CBZ-N-amido-dPEG®36-acid works well in solution-phase synthesis. Carbodiimide activation, with or without an acylating agent, permits conjugation of the acid terminus of the dPEG® product to free amines. Other synthetic processes (e.g., surface modification, supramolecular construction) requiring the attachment or insertion of a medium-length PEG linker or spacer can employ CBZ-N-amido-dPEG®36-acid profitably also.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 1809.12; single compound
Chemical formula C₈₃H₁₅₇NO₄₀
CAS 1334177-88-6
Purity > 98%
Spacers dPEG® Spacer is 111 atoms and 132.7 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, DMAC or DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post CBZ-N-amido-dPEG®₃₆-acid appeared first on VectorLabs.

]]>

Description

CBZ-N-amido-dPEG®36-acid, product number QBD-10906, is a benzyl carbamate (Cbz) N-protected amino-dPEG®-acid that provides a long (111 atoms, 132.7 Å), single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis to modify the side chain of lysine and in other forms of supramolecular construction. The Cbz protecting group is stable to acidic and basic conditions and is most easily removed using palladium black or palladium on carbon with hydrogen. This makes Cbz removal orthogonal to most other peptide synthesis deprotection reactions.

CBZ-N-amido-dPEG®36-acid works well in solution-phase synthesis. Carbodiimide activation, with or without an acylating agent, permits conjugation of the acid terminus of the dPEG® product to free amines. Other synthetic processes (e.g., surface modification, supramolecular construction) requiring the attachment or insertion of a medium-length PEG linker or spacer can employ CBZ-N-amido-dPEG®36-acid profitably also.

Specifications

Unit Size100mg, 1000mg
Molecular Weight1809.12; single compound
Chemical formulaC₈₃H₁₅₇NO₄₀
CAS1334177-88-6
Purity> 98%
SpacersdPEG® Spacer is 111 atoms and 132.7 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, DMAC or DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post CBZ-N-amido-dPEG®₃₆-acid appeared first on VectorLabs.

]]> CBZ-N-amido-dPEG®₂₄-acid https://staging.vectorlabs.com/products/cbz-n-amido-dpeg24-acid/ Sat, 24 Feb 2024 02:09:58 +0000 https://staging.vectorlabs.com/?post_type=product&p=35952 CBZ-N-amido-dPEG®24-acid, product number QBD-10316, is a benzyl carbamate (Cbz) N-protected amino-dPEG®-acid that provides a long (76 atoms), single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis to modify the side chain of lysine and in other forms of supramolecular construction. The Cbz protecting group is stable to acidic and basic conditions and is most easily removed using palladium black or palladium on carbon with hydrogen. This makes Cbz removal orthogonal to most other peptide synthesis deprotection reactions.

CBZ-N-amido-dPEG®24-acid works well in solution-phase synthesis. Carbodiimide activation, with or without an acylating agent, permits conjugation of the acid terminus of the dPEG® product to free amines. Other synthetic processes (e.g., surface modification, supramolecular construction) requiring the attachment or insertion of a medium-length PEG linker or spacer can employ CBZ-N-amido-dPEG®24-acid profitably also.

Unit Size 100 mg, 1000 mg
Molecular Weight 1280.49; single compound
Chemical formula C₅₉H₁₀₉NO₂₈
CAS 1334177-88-6
Purity > 97%
Spacers dPEG® Spacer is 76 atoms and 88.5 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, DMAC or DMSO.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post CBZ-N-amido-dPEG®₂₄-acid appeared first on VectorLabs.

]]>

Description

CBZ-N-amido-dPEG®24-acid, product number QBD-10316, is a benzyl carbamate (Cbz) N-protected amino-dPEG®-acid that provides a long (76 atoms), single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis to modify the side chain of lysine and in other forms of supramolecular construction. The Cbz protecting group is stable to acidic and basic conditions and is most easily removed using palladium black or palladium on carbon with hydrogen. This makes Cbz removal orthogonal to most other peptide synthesis deprotection reactions.

CBZ-N-amido-dPEG®24-acid works well in solution-phase synthesis. Carbodiimide activation, with or without an acylating agent, permits conjugation of the acid terminus of the dPEG® product to free amines. Other synthetic processes (e.g., surface modification, supramolecular construction) requiring the attachment or insertion of a medium-length PEG linker or spacer can employ CBZ-N-amido-dPEG®24-acid profitably also.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight1280.49; single compound
Chemical formulaC₅₉H₁₀₉NO₂₈
CAS1334177-88-6
Purity> 97%
SpacersdPEG® Spacer is 76 atoms and 88.5 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, DMAC or DMSO.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post CBZ-N-amido-dPEG®₂₄-acid appeared first on VectorLabs.

]]> CBZ-N-amido-dPEG®₁₂-acid https://staging.vectorlabs.com/products/cbz-n-amido-dpeg12-acid/ Sat, 24 Feb 2024 02:09:41 +0000 https://staging.vectorlabs.com/?post_type=product&p=35785 CBZ-N-amido-dPEG®12-acid, product number QBD-10286, is a benzyl carbamate (Cbz) N-protected amino-dPEG®-acid that provides a medium-length (40 atoms), single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis to modify the side chain of lysine and in other forms of supramolecular construction. The Cbz protecting group is stable to acidic and basic conditions and is most easily removed using palladium black or palladium on carbon with hydrogen. This makes Cbz removal orthogonal to most other peptide synthesis deprotection reactions.

CBZ-N-amido-dPEG®12-acid works well in solution-phase synthesis. Carbodiimide activation, with or without an acylating agent, permits conjugation of the acid terminus of the dPEG® product to free amines. Other synthetic processes (e.g., surface modification, supramolecular construction) requiring the attachment or insertion of a medium-length PEG linker or spacer can employ CBZ-N-amido-dPEG®12-acid profitably also.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 751.86; single compound
Chemical formula C₃₅H₆₁NO₁₆
CAS 1334177-88-6
Purity > 98%
Spacers dPEG® Spacer is 40 atoms and 46.5 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, DMAC, or DMSO.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post CBZ-N-amido-dPEG®₁₂-acid appeared first on VectorLabs.

]]>

Description

CBZ-N-amido-dPEG®12-acid, product number QBD-10286, is a benzyl carbamate (Cbz) N-protected amino-dPEG®-acid that provides a medium-length (40 atoms), single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis to modify the side chain of lysine and in other forms of supramolecular construction. The Cbz protecting group is stable to acidic and basic conditions and is most easily removed using palladium black or palladium on carbon with hydrogen. This makes Cbz removal orthogonal to most other peptide synthesis deprotection reactions.

CBZ-N-amido-dPEG®12-acid works well in solution-phase synthesis. Carbodiimide activation, with or without an acylating agent, permits conjugation of the acid terminus of the dPEG® product to free amines. Other synthetic processes (e.g., surface modification, supramolecular construction) requiring the attachment or insertion of a medium-length PEG linker or spacer can employ CBZ-N-amido-dPEG®12-acid profitably also.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight751.86; single compound
Chemical formulaC₃₅H₆₁NO₁₆
CAS1334177-88-6
Purity> 98%
SpacersdPEG® Spacer is 40 atoms and 46.5 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, DMAC, or DMSO.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post CBZ-N-amido-dPEG®₁₂-acid appeared first on VectorLabs.

]]> CBZ-N-amido-dPEG®₈-acid https://staging.vectorlabs.com/products/cbz-n-amido-dpeg8-acid/ Sat, 24 Feb 2024 02:07:58 +0000 https://staging.vectorlabs.com/?post_type=product&p=35729 CBZ-N-amido-dPEG®8-acid, product number QBD-10276, is a benzyl carbamate (Cbz) N-protected amino-dPEG®-acid that provides a short, single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis to modify the side chain of lysine and in other forms of supramolecular construction. The Cbz protecting group is stable to acidic and basic conditions and is most easily removed using palladium black or palladium on carbon with hydrogen. This makes Cbz removal orthogonal to most other peptide synthesis deprotection reactions.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 575.65; single compound
Chemical formula C₂₇H₄₅NO₁₂
CAS 1334177-87-5
Purity > 98%
Spacers dPEG® Spacer is 28 atoms and 32.2 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, DMAC or DMSO.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post CBZ-N-amido-dPEG®₈-acid appeared first on VectorLabs.

]]>

Description

CBZ-N-amido-dPEG®8-acid, product number QBD-10276, is a benzyl carbamate (Cbz) N-protected amino-dPEG®-acid that provides a short, single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis to modify the side chain of lysine and in other forms of supramolecular construction. The Cbz protecting group is stable to acidic and basic conditions and is most easily removed using palladium black or palladium on carbon with hydrogen. This makes Cbz removal orthogonal to most other peptide synthesis deprotection reactions.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight575.65; single compound
Chemical formulaC₂₇H₄₅NO₁₂
CAS1334177-87-5
Purity> 98%
SpacersdPEG® Spacer is 28 atoms and 32.2 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, DMAC or DMSO.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post CBZ-N-amido-dPEG®₈-acid appeared first on VectorLabs.

]]> CBZ-N-amido-dPEG®₄-acid https://staging.vectorlabs.com/products/cbz-n-amido-dpeg4-acid/ Sat, 24 Feb 2024 02:07:49 +0000 https://staging.vectorlabs.com/?post_type=product&p=35676 CBZ-N-amido-dPEG®4-acid, product number QBD-10268, is a benzyl carbamate (Cbz) N-protected amino-dPEG®-acid that provides a short, single molecular weight discrete PEG (dPEG®) spacer. Designed for use in peptide synthesis, it can also be used in many other reactions. In peptide synthesis, the removal of the Cbz protecting group is orthogonal to many other protecting groups.

The Cbz protecting group (also called the Z protecting group) is one of the most popular protecting groups for amines. It is stable in mildly basic and acidic conditions. A variety of methods cleave the Cbz group. The most popular cleavage technique is hydrogenolysis, using palladium black or palladium on carbon.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 399.44; single compound
Chemical formula C₁₉H₂₉NO₈
CAS 756526-00-8
Purity > 98%
Spacers dPEG® Spacer is 17 atoms and 19.2 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, DMAC or DMSO.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post CBZ-N-amido-dPEG®₄-acid appeared first on VectorLabs.

]]>

Description

CBZ-N-amido-dPEG®4-acid, product number QBD-10268, is a benzyl carbamate (Cbz) N-protected amino-dPEG®-acid that provides a short, single molecular weight discrete PEG (dPEG®) spacer. Designed for use in peptide synthesis, it can also be used in many other reactions. In peptide synthesis, the removal of the Cbz protecting group is orthogonal to many other protecting groups.

The Cbz protecting group (also called the Z protecting group) is one of the most popular protecting groups for amines. It is stable in mildly basic and acidic conditions. A variety of methods cleave the Cbz group. The most popular cleavage technique is hydrogenolysis, using palladium black or palladium on carbon.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight399.44; single compound
Chemical formulaC₁₉H₂₉NO₈
CAS756526-00-8
Purity> 98%
SpacersdPEG® Spacer is 17 atoms and 19.2 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, DMAC or DMSO.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post CBZ-N-amido-dPEG®₄-acid appeared first on VectorLabs.

]]> CBZ-N-amido-dPEG®₆-acid https://staging.vectorlabs.com/products/cbz-n-amido-dpeg6-acid/ Sat, 24 Feb 2024 02:04:43 +0000 https://staging.vectorlabs.com/?post_type=product&p=34934 CBZ-N-amido-dPEG®6-acid, product number QBD-10066, is a benzyl carbamate (Cbz) N-protected amino-dPEG®-acid that provides a short, single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis as well as in many other reactions. In peptide synthesis, removal of the Cbz protecting group is orthogonal to many other protecting groups.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 487.54; single compound
Chemical formula C₂₃H₃₇NO₁₀
CAS 1334177-80-8
Purity > 98%
Spacers dPEG® Spacer is 22 atoms and 25.1 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, DMAC or DMSO.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post CBZ-N-amido-dPEG®₆-acid appeared first on VectorLabs.

]]>

Description

CBZ-N-amido-dPEG®6-acid, product number QBD-10066, is a benzyl carbamate (Cbz) N-protected amino-dPEG®-acid that provides a short, single molecular weight discrete PEG (dPEG®) spacer. It can be used in peptide synthesis as well as in many other reactions. In peptide synthesis, removal of the Cbz protecting group is orthogonal to many other protecting groups.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 487.54; single compound
Chemical formula C₂₃H₃₇NO₁₀
CAS 1334177-80-8
Purity > 98%
Spacers dPEG® Spacer is 22 atoms and 25.1 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, DMAC or DMSO.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

Documents

References

  1. Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post CBZ-N-amido-dPEG®₆-acid appeared first on VectorLabs.

]]>