Amine Reactive – VectorLabs https://staging.vectorlabs.com From linker design and synthesis, bioconjugated design and manufacturing, biomolecule labeling and functionalization, and detection system and solutions, our team is here to help you move forward, with impact. Wed, 22 Oct 2025 17:21:08 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.3 https://staging.vectorlabs.com/wp-content/uploads/2024/11/V-favicon-02-100x100.png Amine Reactive – VectorLabs https://staging.vectorlabs.com 32 32 m-dPEG®₂₅-NHS ester https://staging.vectorlabs.com/products/m-dpeg25-nhs-ester/ Sat, 24 Feb 2024 02:16:35 +0000 https://staging.vectorlabs.com/?post_type=product&p=39359 m-dPEG®25-NHS ester, product number QBD-11291, is a long (77 atoms, 89.9 Å), methyl-terminated, discrete-chain-length polyethylene glycol (dPEG®) spacer functionalized with an N-hydroxysuccinimidyl (NHS) ester for reaction with free amines. m-dPEG®25-NHS ester is just one member of an comprehensive line of methyl-terminated PEGylation reagents that includes dPEG® spacers containing 2 to 49 ethylene glycol units.

NHS esters react optimally with free amines at pH 7.0 – 7.5. In aqueous media, the hydrolytic rate of the ester to the carboxylic acid increases with increasing pH. Reacting surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Many applications could employ m-dPEG®25-NHS ester, including the following:
dendrimer construction;
PK and immunogenicity improvements for dendrimers, peptides, and proteins;
cell surface engineering;
peptide synthesis and modification to improve water solubility or decrease immunogenicity;
coating of nanoparticles, quantum dots, and carbon nanotubes; and
prevention of protein aggregation.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 1258.44; single compound
Chemical formula C₅₆H₁₀₇NO₂₉
CAS N/A
Purity > 98%
Spacers dPEG® Spacer is 77 atoms and 89.9 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) DCM, Methanol, Ethanol, Acetonitrile, Water, Ethyle Acetate, or Acetone.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

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Description

m-dPEG®25-NHS ester, product number QBD-11291, is a long (77 atoms, 89.9 Å), methyl-terminated, discrete-chain-length polyethylene glycol (dPEG®) spacer functionalized with an N-hydroxysuccinimidyl (NHS) ester for reaction with free amines. m-dPEG®25-NHS ester is just one member of an comprehensive line of methyl-terminated PEGylation reagents that includes dPEG® spacers containing 2 to 49 ethylene glycol units.

NHS esters react optimally with free amines at pH 7.0 – 7.5. In aqueous media, the hydrolytic rate of the ester to the carboxylic acid increases with increasing pH. Reacting surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Many applications could employ m-dPEG®25-NHS ester, including the following:
dendrimer construction;
PK and immunogenicity improvements for dendrimers, peptides, and proteins;
cell surface engineering;
peptide synthesis and modification to improve water solubility or decrease immunogenicity;
coating of nanoparticles, quantum dots, and carbon nanotubes; and
prevention of protein aggregation.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight1258.44; single compound
Chemical formulaC₅₆H₁₀₇NO₂₉
CASN/A
Purity> 98%
SpacersdPEG® Spacer is 77 atoms and 89.9 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)DCM, Methanol, Ethanol, Acetonitrile, Water, Ethyle Acetate, or Acetone.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full overview of the dPEG® products.

The post m-dPEG®₂₅-NHS ester appeared first on VectorLabs.

]]> m-dPEG®₂₅-TFP ester https://staging.vectorlabs.com/products/m-dpeg25-tfp-ester/ Sat, 24 Feb 2024 02:16:33 +0000 https://staging.vectorlabs.com/?post_type=product&p=39351 m-dPEG®25-TFP ester, product number QBD-11290, is a long (77 atoms, 89.9 Å), methyl-terminated, discrete-chain-length polyethylene glycol (dPEG®) spacer functionalized with a 2,3,5,6-tetrafluorophenyl (TFP) ester for reaction with free amines. m-dPEG®25-TFP ester is just one member of an comprehensive line of methyl-terminated PEGylation reagents that includes dPEG® spacers containing 2 to 49 ethylene glycol units.

TFP esters react optimally with free amines at pH 7.5 – 8.0 and are generally more hydrolytically stable in water and aqueous buffers than NHS esters. In aqueous media, the hydrolytic rate of the ester to the carboxylic acid increases with increasing pH. Reacting surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Many applications could employ m-dPEG®25-TFP ester, including the following:
dendrimer construction;
PK and immunogenicity improvements for dendrimers, peptides, and proteins;
cell surface engineering;
peptide synthesis and modification to improve water solubility or decrease immunogenicity;
coating of nanoparticles, quantum dots, and carbon nanotubes; and
prevention of protein aggregation.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 1309.42; single compound
Chemical formula C₅₈H₁₀₄F₄O₂₇
CAS N/A
Purity > 98%
Spacers dPEG® Spacer is 77 atoms and 89.9 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) DCM, Methanol, Ethanol, Acetonitrile, Water, Ethyle Acetate, or Acetone.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₂₅-TFP ester appeared first on VectorLabs.

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Description

m-dPEG®25-TFP ester, product number QBD-11290, is a long (77 atoms, 89.9 Å), methyl-terminated, discrete-chain-length polyethylene glycol (dPEG®) spacer functionalized with a 2,3,5,6-tetrafluorophenyl (TFP) ester for reaction with free amines. m-dPEG®25-TFP ester is just one member of an comprehensive line of methyl-terminated PEGylation reagents that includes dPEG® spacers containing 2 to 49 ethylene glycol units.

TFP esters react optimally with free amines at pH 7.5 – 8.0 and are generally more hydrolytically stable in water and aqueous buffers than NHS esters. In aqueous media, the hydrolytic rate of the ester to the carboxylic acid increases with increasing pH. Reacting surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Many applications could employ m-dPEG®25-TFP ester, including the following:
dendrimer construction;
PK and immunogenicity improvements for dendrimers, peptides, and proteins;
cell surface engineering;
peptide synthesis and modification to improve water solubility or decrease immunogenicity;
coating of nanoparticles, quantum dots, and carbon nanotubes; and
prevention of protein aggregation.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight1309.42; single compound
Chemical formulaC₅₈H₁₀₄F₄O₂₇
CASN/A
Purity> 98%
SpacersdPEG® Spacer is 77 atoms and 89.9 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)DCM, Methanol, Ethanol, Acetonitrile, Water, Ethyle Acetate, or Acetone.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full overview of the dPEG® products.

The post m-dPEG®₂₅-TFP ester appeared first on VectorLabs.

]]> m-dPEG®₂₅-acid https://staging.vectorlabs.com/products/m-dpeg25-acid/ Sat, 24 Feb 2024 02:16:32 +0000 https://staging.vectorlabs.com/?post_type=product&p=39343 m-dPEG®25-acid, product number QBD-11289, is a long (77 atoms, 89.9 Å), methyl-capped, discrete chain length polyethylene glycol (dPEG®) spacer that terminates in a propionic acid group. The terminal propionic acid moiety can be coupled directly to free amines using EDC or another carbodiimide. Alternatively, the reactive end can be converted into an active ester that can then be conjugated to free amines. N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), and 2,3,4,5,6-pentafluorophenol (PFP) typically are used for this purpose.

m-dPEG®25-acid can modify amine-functionalized surfaces (carbon nanotubes, other nanoparticles, quantum dots, etc.) or free amines on biomolecules. When used to coat surfaces or modify biomolecules, m-dPEG®25-acid reduces or eliminates non-specific binding, increases the hydrodynamic volume and water solubility of the conjugate molecule. Please note that modifying the surface amines of biomolecules with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Specifications

Unit Size 100 mg, 1000 mg
Molecular Weight 1161.37; single compound;
Chemical formula C₅₂H₁₀₄O₂₇
CAS N/A
Purity > 98%
Spacers dPEG® Spacer is 77 atoms and 89.9 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₂₅-acid appeared first on VectorLabs.

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Description

m-dPEG®25-acid, product number QBD-11289, is a long (77 atoms, 89.9 Å), methyl-capped, discrete chain length polyethylene glycol (dPEG®) spacer that terminates in a propionic acid group. The terminal propionic acid moiety can be coupled directly to free amines using EDC or another carbodiimide. Alternatively, the reactive end can be converted into an active ester that can then be conjugated to free amines. N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), and 2,3,4,5,6-pentafluorophenol (PFP) typically are used for this purpose.

m-dPEG®25-acid can modify amine-functionalized surfaces (carbon nanotubes, other nanoparticles, quantum dots, etc.) or free amines on biomolecules. When used to coat surfaces or modify biomolecules, m-dPEG®25-acid reduces or eliminates non-specific binding, increases the hydrodynamic volume and water solubility of the conjugate molecule. Please note that modifying the surface amines of biomolecules with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Specifications

Unit Size100 mg, 1000 mg
Molecular Weight1161.37; single compound;
Chemical formulaC₅₂H₁₀₄O₂₇
CASN/A
Purity> 98%
SpacersdPEG® Spacer is 77 atoms and 89.9 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 2nd Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0). Specifically see pp. 726-729 in his Chapter 18 on discrete PEG compounds for pegylation applications.

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full overview of the dPEG® products.

The post m-dPEG®₂₅-acid appeared first on VectorLabs.

]]> m-dPEG®₂₅-amido-dPEG®₂₄-acid https://staging.vectorlabs.com/products/m-dpeg25-amido-dpeg24-acid/ Sat, 24 Feb 2024 02:14:57 +0000 https://staging.vectorlabs.com/?post_type=product&p=37463 m-dPEG®25-amido-dPEG®24-acid, product number QBD-11097, is a long (153 atoms, 179.8 Å), methyl-capped, discrete chain length polyethylene glycol (dPEG®) spacer. The effective length of the dPEG® spacer is about 49 ethylene oxide units (i.e., m-dPEG®49-acid) with an amide bond in the middle of the chain. The reactive end of the molecule terminates in a propionic acid group. The terminal propionic acid moiety can be coupled directly to free amines using EDC or another carbodiimide. Alternatively, converting the reactive end into an active ester permits the conjugation of the transformed product to free amines. N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), and 2,3,4,5,6-pentafluorophenol (PFP) are typically used for this purpose.

m-dPEG®25-amido-dPEG®24-acid, QBD-11097, reacts with amine-functionalized surfaces (carbon nanotubes, nanoparticles made of silica or various metals, quantum dots, and similar types of products) or free amines on biomolecules. When used to coat surfaces or modify biomolecules, m-dPEG®25-amido-dPEG®24-acid reduces or eliminates non-specific binding and increases water solubility. Crucially, the elimination of non-specific binding may increase the signal-to-noise ratio in imaging applications and assays where this is a consideration. Please note that modifying the surface amines of biomolecules with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 2289.71; single compound
Chemical formula C₁₀₃H₂₀₅NO₅₂
CAS N/A
Purity > 98%
Spacers dPEG® Spacer is 153 atoms and 179.8 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Water, Methylene Chloride, Methanol, Acetonitrile, Dimethylformamide, or Dimethylacetamide
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₂₅-amido-dPEG®₂₄-acid appeared first on VectorLabs.

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Description

m-dPEG®25-amido-dPEG®24-acid, product number QBD-11097, is a long (153 atoms, 179.8 Å), methyl-capped, discrete chain length polyethylene glycol (dPEG®) spacer. The effective length of the dPEG® spacer is about 49 ethylene oxide units (i.e., m-dPEG®49-acid) with an amide bond in the middle of the chain. The reactive end of the molecule terminates in a propionic acid group. The terminal propionic acid moiety can be coupled directly to free amines using EDC or another carbodiimide. Alternatively, converting the reactive end into an active ester permits the conjugation of the transformed product to free amines. N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), and 2,3,4,5,6-pentafluorophenol (PFP) are typically used for this purpose.

m-dPEG®25-amido-dPEG®24-acid, QBD-11097, reacts with amine-functionalized surfaces (carbon nanotubes, nanoparticles made of silica or various metals, quantum dots, and similar types of products) or free amines on biomolecules. When used to coat surfaces or modify biomolecules, m-dPEG®25-amido-dPEG®24-acid reduces or eliminates non-specific binding and increases water solubility. Crucially, the elimination of non-specific binding may increase the signal-to-noise ratio in imaging applications and assays where this is a consideration. Please note that modifying the surface amines of biomolecules with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Specifications

Unit Size100mg, 1000mg
Molecular Weight2289.71; single compound
Chemical formulaC₁₀₃H₂₀₅NO₅₂
CASN/A
Purity> 98%
SpacersdPEG® Spacer is 153 atoms and 179.8 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Water, Methylene Chloride, Methanol, Acetonitrile, Dimethylformamide, or Dimethylacetamide
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 2nd Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0). Specifically see pp. 726-729 in his Chapter 18 on discrete PEG compounds for pegylation applications.

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full overview of the dPEG® products.

The post m-dPEG®₂₅-amido-dPEG®₂₄-acid appeared first on VectorLabs.

]]> m-dPEG®₂₅-amido-dPEG®₂₄-TFP ester https://staging.vectorlabs.com/products/m-dpeg25-amido-dpeg24-tfp-ester/ Sat, 24 Feb 2024 02:14:56 +0000 https://staging.vectorlabs.com/?post_type=product&p=37455 m-dPEG®25-amido-dPEG®24-TFP ester, product number QBD-11096, is a long (153 atoms, 178.9 Å), methyl-terminated, discrete-chain-length polyethylene glycol (dPEG®) spacer functionalized with a 2,3,5,6-tetrafluorophenyl (TFP) ester for reaction with free amines. It is effectively a single molecular weight mPEG49 linker with an amide linkage in the middle of the discrete PEG chain. m-dPEG®25-amido-dPEG®24-TFP ester is just one member of an comprehensive line of methyl-terminated PEGylation reagents that includes dPEG® spacers containing 2 to 49 ethylene glycol units.

TFP esters react optimally with free amines at pH 7.5 – 8.0 and are generally more hydrolytically stable in water and aqueous buffers than NHS esters. In aqueous media, the hydrolytic rate of the ester to the carboxylic acid increases with increasing pH. Reacting surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Many applications could employ m-dPEG®25-amido-dPEG®24-TFP ester, including the following:
dendrimer construction;
PK and immunogenicity improvements for dendrimers, peptides, and proteins;
cell surface engineering;
peptide synthesis and modification to improve water solubility or decrease immunogenicity;
coating of nanoparticles, quantum dots, and carbon nanotubes; and
prevention of protein aggregation.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 2437.76; single compound
Chemical formula C₁₀₉H₂₀₅F₄NO₅₂
CAS N/A
Purity > 98%
Spacers dPEG® Spacer is 153 atoms and 178.9 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Water, Dimethylacetamide, Acetonitrile, or Methylene Chloride
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₂₅-amido-dPEG®₂₄-TFP ester appeared first on VectorLabs.

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Description

m-dPEG®25-amido-dPEG®24-TFP ester, product number QBD-11096, is a long (153 atoms, 178.9 Å), methyl-terminated, discrete-chain-length polyethylene glycol (dPEG®) spacer functionalized with a 2,3,5,6-tetrafluorophenyl (TFP) ester for reaction with free amines. It is effectively a single molecular weight mPEG49 linker with an amide linkage in the middle of the discrete PEG chain. m-dPEG®25-amido-dPEG®24-TFP ester is just one member of an comprehensive line of methyl-terminated PEGylation reagents that includes dPEG® spacers containing 2 to 49 ethylene glycol units.

TFP esters react optimally with free amines at pH 7.5 – 8.0 and are generally more hydrolytically stable in water and aqueous buffers than NHS esters. In aqueous media, the hydrolytic rate of the ester to the carboxylic acid increases with increasing pH. Reacting surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Many applications could employ m-dPEG®25-amido-dPEG®24-TFP ester, including the following:
dendrimer construction;
PK and immunogenicity improvements for dendrimers, peptides, and proteins;
cell surface engineering;
peptide synthesis and modification to improve water solubility or decrease immunogenicity;
coating of nanoparticles, quantum dots, and carbon nanotubes; and
prevention of protein aggregation.

Specifications

Unit Size100mg, 1000mg
Molecular Weight2437.76; single compound
Chemical formulaC₁₀₉H₂₀₅F₄NO₅₂
CASN/A
Purity> 98%
SpacersdPEG® Spacer is 153 atoms and 178.9 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Water, Dimethylacetamide, Acetonitrile, or Methylene Chloride
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 2nd Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0). Specifically see pp. 726-729 in his Chapter 18 on discrete PEG compounds for pegylation applications.

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full overview of the dPEG® products.

The post m-dPEG®₂₅-amido-dPEG®₂₄-TFP ester appeared first on VectorLabs.

]]> m-dPEG®₁₃-TFP ester https://staging.vectorlabs.com/products/m-dpeg13-tfp-ester/ Sat, 24 Feb 2024 02:14:51 +0000 https://staging.vectorlabs.com/?post_type=product&p=37417 m-dPEG®13-TFP ester, product number QBD-11087, is a medium-length (41 atoms, 47.3 Å), methyl-terminated, discrete-chain-length polyethylene glycol (dPEG®) spacer functionalized with a 2,3,5,6-tetrafluorophenyl (TFP) ester for reaction with free amines. m-dPEG®13-TFP ester is just one member of an comprehensive line of methyl-terminated dPEG® products that includes dPEG® spacers containing 2 to 49 ethylene glycol units.

TFP esters react optimally with free amines at pH 7.5 – 8.0 and are generally more hydrolytically stable in water and aqueous buffers than NHS esters. In aqueous media, the hydrolytic rate of the ester to the carboxylic acid increases with increasing pH. Reacting surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Many applications could employ m-dPEG®13-TFP ester, including the following:
vaccine development (modifying the immunogenicity of biomolecules);
dendrimer construction;
PK and immunogenicity improvements for dendrimers, peptides, and proteins;
cell surface engineering;
peptide synthesis and modification to improve water solubility or decrease immunogenicity;
coating of nanoparticles, quantum dots, and carbon nanotubes; and
prevention of protein aggregation.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 780.793; single compound
Chemical formula C₃₄H₅₆F₄O₁₅
CAS N/A
Purity > 98%
Spacers dPEG® Spacer is 41 atoms and 47.3 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene Chloride, Acetone, Methanol, Acetonitrile, Ethyl Acetate, DMSO, DMAC, or DMF.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₁₃-TFP ester appeared first on VectorLabs.

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Description

m-dPEG®13-TFP ester, product number QBD-11087, is a medium-length (41 atoms, 47.3 Å), methyl-terminated, discrete-chain-length polyethylene glycol (dPEG®) spacer functionalized with a 2,3,5,6-tetrafluorophenyl (TFP) ester for reaction with free amines. m-dPEG®13-TFP ester is just one member of an comprehensive line of methyl-terminated dPEG® products that includes dPEG® spacers containing 2 to 49 ethylene glycol units.

TFP esters react optimally with free amines at pH 7.5 – 8.0 and are generally more hydrolytically stable in water and aqueous buffers than NHS esters. In aqueous media, the hydrolytic rate of the ester to the carboxylic acid increases with increasing pH. Reacting surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Many applications could employ m-dPEG®13-TFP ester, including the following:
vaccine development (modifying the immunogenicity of biomolecules);
dendrimer construction;
PK and immunogenicity improvements for dendrimers, peptides, and proteins;
cell surface engineering;
peptide synthesis and modification to improve water solubility or decrease immunogenicity;
coating of nanoparticles, quantum dots, and carbon nanotubes; and
prevention of protein aggregation.

Specifications

Unit Size100mg, 1000mg
Molecular Weight780.793; single compound
Chemical formulaC₃₄H₅₆F₄O₁₅
CASN/A
Purity> 98%
SpacersdPEG® Spacer is 41 atoms and 47.3 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene Chloride, Acetone, Methanol, Acetonitrile, Ethyl Acetate, DMSO, DMAC, or DMF.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 2nd Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0). Specifically see pp. 726-729 in his Chapter 18 on discrete PEG compounds for pegylation applications.

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full overview of the dPEG® products.

The post m-dPEG®₁₃-TFP ester appeared first on VectorLabs.

]]> m-dPEG®₁₃-NHS ester https://staging.vectorlabs.com/products/m-dpeg13-nhs-ester/ Sat, 24 Feb 2024 02:14:50 +0000 https://staging.vectorlabs.com/?post_type=product&p=37409 m-dPEG®13-NHS ester, product number QBD-11086, is a medium-length (41 atoms, 47.3 Å), methyl-terminated, discrete-chain-length polyethylene glycol (dPEG®) spacer functionalized with an N-hydroxysuccinimidyl (NHS) ester for reaction with free amines. m-dPEG®13-NHS ester is just one member of a comprehensive line of methyl-terminated dPEG® products that includes dPEG® spacers containing 2 to 49 ethylene glycol units.

NHS esters react optimally with free amines at pH 7.0 – 7.5. In aqueous media, the hydrolytic rate of the ester to the carboxylic acid increases with increasing pH. Reacting surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.
Many applications could employ m-dPEG®13-NHS ester, including the following:
vaccine development (modifying the immunogenicity of biomolecules);
dendrimer construction;
PK and immunogenicity improvements for dendrimers, peptides, and proteins;
cell surface engineering;
peptide synthesis and modification to improve water solubility or decrease immunogenicity;
coating of nanoparticles, quantum dots, and carbon nanotubes; and
prevention of protein aggregation.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 729.807; single compound
Chemical formula C₃₂H₅₉NO₁₇
CAS N/A
Purity > 98%
Spacers dPEG® Spacer is 41 atoms and 47.3 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene Chloride, DMSO, Acetonitrile, Acetone, Methanol, Ethyl Acetate, DMAC, or DMF.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₁₃-NHS ester appeared first on VectorLabs.

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Description

m-dPEG®13-NHS ester, product number QBD-11086, is a medium-length (41 atoms, 47.3 Å), methyl-terminated, discrete-chain-length polyethylene glycol (dPEG®) spacer functionalized with an N-hydroxysuccinimidyl (NHS) ester for reaction with free amines. m-dPEG®13-NHS ester is just one member of a comprehensive line of methyl-terminated dPEG® products that includes dPEG® spacers containing 2 to 49 ethylene glycol units.

NHS esters react optimally with free amines at pH 7.0 – 7.5. In aqueous media, the hydrolytic rate of the ester to the carboxylic acid increases with increasing pH. Reacting surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.
Many applications could employ m-dPEG®13-NHS ester, including the following:
vaccine development (modifying the immunogenicity of biomolecules);
dendrimer construction;
PK and immunogenicity improvements for dendrimers, peptides, and proteins;
cell surface engineering;
peptide synthesis and modification to improve water solubility or decrease immunogenicity;
coating of nanoparticles, quantum dots, and carbon nanotubes; and
prevention of protein aggregation.

Specifications

Unit Size100mg, 1000mg
Molecular Weight729.807; single compound
Chemical formulaC₃₂H₅₉NO₁₇
CASN/A
Purity> 98%
SpacersdPEG® Spacer is 41 atoms and 47.3 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene Chloride, DMSO, Acetonitrile, Acetone, Methanol, Ethyl Acetate, DMAC, or DMF.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 2nd Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0). Specifically see pp. 726-729 in his Chapter 18 on discrete PEG compounds for pegylation applications.

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full overview of the dPEG® products.

The post m-dPEG®₁₃-NHS ester appeared first on VectorLabs.

]]> m-dPEG®₁₃-acid https://staging.vectorlabs.com/products/m-dpeg13-acid/ Sat, 24 Feb 2024 02:14:49 +0000 https://staging.vectorlabs.com/?post_type=product&p=37398 m-dPEG®13-acid, product number QBD-11085, is a medium-length (41 atoms, 48.5 Å), methyl-capped, discrete chain length polyethylene glycol (dPEG®) spacer that terminates in a propionic acid group. The terminal propionic acid moiety can be coupled directly to free amines using EDC or another carbodiimide. Alternatively, the reactive end can be converted into an active ester that can then be conjugated to free amines. N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), and 2,3,4,5,6-pentafluorophenol (PFP) typically are used for this purpose.

m-dPEG®13-acid can modify amine-functionalized surfaces (carbon nanotubes, other nanoparticles, quantum dots, etc.) or free amines on biomolecules. When used to coat surfaces or modify biomolecules, m-dPEG®13-acid reduces or eliminates non-specific binding, increases the hydrodynamic volume and water solubility of the conjugate molecule. Please note that modifying the surface amines of biomolecules with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 632.74; single compound
Chemical formula C₂₈H₅₆O₁₅
CAS N/A
Purity > 95%
Spacers dPEG® Spacer is 41atoms and 48.530 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene Chloride, Acetonitrile, Acetone, DMSO, Methanol, THF, or Water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₁₃-acid appeared first on VectorLabs.

]]>

Description

m-dPEG®13-acid, product number QBD-11085, is a medium-length (41 atoms, 48.5 Å), methyl-capped, discrete chain length polyethylene glycol (dPEG®) spacer that terminates in a propionic acid group. The terminal propionic acid moiety can be coupled directly to free amines using EDC or another carbodiimide. Alternatively, the reactive end can be converted into an active ester that can then be conjugated to free amines. N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), and 2,3,4,5,6-pentafluorophenol (PFP) typically are used for this purpose.

m-dPEG®13-acid can modify amine-functionalized surfaces (carbon nanotubes, other nanoparticles, quantum dots, etc.) or free amines on biomolecules. When used to coat surfaces or modify biomolecules, m-dPEG®13-acid reduces or eliminates non-specific binding, increases the hydrodynamic volume and water solubility of the conjugate molecule. Please note that modifying the surface amines of biomolecules with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Specifications

Unit Size100mg, 1000mg
Molecular Weight632.74; single compound
Chemical formulaC₂₈H₅₆O₁₅
CASN/A
Purity> 95%
SpacersdPEG® Spacer is 41atoms and 48.530 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene Chloride, Acetonitrile, Acetone, DMSO, Methanol, THF, or Water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

 



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

New optical probes for the continuous monitoring of renal function. Richard B. Dorshow, Bethel Asmelash, Lori K. Chinen, Martin P. Debreczeny, Richard M. Fitch, John N. Freskos, Karen P. Galen, Kimberly R. Gaston, Timothy A. Marzan, Amruta R. Poreddy, Raghavan Rajagopalan, Jeng-Jong Shieh, William L. Neumann. Proc. SPIE 6867, Molecular Probes for Biomedical Applications II. 2008. 68670C. February 13,2008. doi:10.1117/12.763697.

The post m-dPEG®₁₃-acid appeared first on VectorLabs.

]]> m-dPEG®₃₇-NHS ester https://staging.vectorlabs.com/products/m-dpeg37-nhs-ester/ Sat, 24 Feb 2024 02:13:47 +0000 https://staging.vectorlabs.com/?post_type=product&p=37162 m-dPEG®37-NHS ester, product number QBD-10910, is a long (112 atoms, 133.9 Å), methyl-terminated, discrete-length polyethylene glycol (dPEG®) spacer functionalized with an N-hydroxysuccinimidyl (NHS) ester to modify surfaces having accessible free amines.

Free amines react optimally with NHS esters in aqueous media at pH 7.0 – 7.5. In aqueous media, the rate at which the ester hydrolyzes to the carboxylic acid increases with increasing pH. Moreover, it should be noted that reacting surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

m-dPEG®37-NHS ester, product number QBD-10910, has been used successfully to modify silica shelled quantum dots used in imaging applications to make them water-soluble. Also, it has been employed to improve the pharmacokinetic (PK) and biodistribution (BD) properties of an antibody that targets an epitope that is found exclusively in adenocarcinomas. Carbon nanotubes and inorganic nanoparticles with amine-functionalized surfaces could also be modified to passivate the surface and make it hydrophilic. Moreover, proteins and other biomolecules conjugated to this product will have higher water solubility, reduced or eliminated antigenicity, reduced propensity to aggregate, and improved PK and BD properties.

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 1787.07; single compound
Chemical formula C₈₀H₁₅₅NO₄₁
CAS 756525-94-7
Purity > 97%
Spacers dPEG® Spacer is 112 atoms and 133.9 Å
Shipping Ambient
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC or DMSO.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.

The post m-dPEG®₃₇-NHS ester appeared first on VectorLabs.

]]>

Description

m-dPEG®37-NHS ester, product number QBD-10910, is a long (112 atoms, 133.9 Å), methyl-terminated, discrete-length polyethylene glycol (dPEG®) spacer functionalized with an N-hydroxysuccinimidyl (NHS) ester to modify surfaces having accessible free amines.

Free amines react optimally with NHS esters in aqueous media at pH 7.0 – 7.5. In aqueous media, the rate at which the ester hydrolyzes to the carboxylic acid increases with increasing pH. Moreover, it should be noted that reacting surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

m-dPEG®37-NHS ester, product number QBD-10910, has been used successfully to modify silica shelled quantum dots used in imaging applications to make them water-soluble. Also, it has been employed to improve the pharmacokinetic (PK) and biodistribution (BD) properties of an antibody that targets an epitope that is found exclusively in adenocarcinomas. Carbon nanotubes and inorganic nanoparticles with amine-functionalized surfaces could also be modified to passivate the surface and make it hydrophilic. Moreover, proteins and other biomolecules conjugated to this product will have higher water solubility, reduced or eliminated antigenicity, reduced propensity to aggregate, and improved PK and BD properties.

Specifications

Unit Size100mg, 1000mg
Molecular Weight1787.07; single compound
Chemical formulaC₈₀H₁₅₅NO₄₁
CAS756525-94-7
Purity> 97%
SpacersdPEG® Spacer is 112 atoms and 133.9 Å
ShippingAmbient
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC or DMSO.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Silica-Shelled Single Quantum Dot Micelles as Imaging Probes with Dual or Multimodality. Rumiana Bakalova, Zhivko Zhelev, Ichio Aoki, Hideki Ohba, Yusuke Imai, and Iwao Kanno. Anal. Chem. 2006, 78 (16) pp 5925–5932. July 14, 2006. DOI: 10.1021/ac060412b.

Engineering PEGylated Antibody Fragments for Enhanced Properties and Cancer Detection. Shubham Mangla. Knowledge Bank. 2016, May 2016.

Tuning surface functionalities of Sub-10 nm-sized nanocarriers to target outer retina in designing drug delivery agents for intravitreal administration. Suyeon You, Hyoungtai Kim, Hye-youn Junga, Boram Kim, Eun Jung Lee, Jin Woo Kim, Yoonkyung Kim. Biomaterials. 2020. DOI: 10.1016/j.biomaterials.2020.120188

The post m-dPEG®₃₇-NHS ester appeared first on VectorLabs.

]]> m-dPEG®₃₇-acid https://staging.vectorlabs.com/products/m-dpeg37-acid/ Sat, 24 Feb 2024 02:13:46 +0000 https://staging.vectorlabs.com/?post_type=product&p=37154 "m-dPEG®37-acid, product number QBD-10909, is a long (112 atoms, 133.9 Å), methyl-capped, discrete chain length polyethylene glycol (dPEG®) spacer that terminates in a propionic acid group. The terminal propionic acid moiety can be coupled directly to free amines using EDC or another carbodiimide. Alternatively, the reactive end can be converted into an active ester that can then be conjugated to free amines. N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), and 2,3,4,5,6-pentafluorophenol (PFP) typically are used for this purpose.

m-dPEG®37-acid can modify amine-functionalized surfaces (carbon nanotubes, other nanoparticles, quantum dots, etc.) or free amines on biomolecules. When used to coat surfaces or modify biomolecules, m-dPEG®37-acid reduces or eliminates non-specific binding, increases the hydrodynamic volume and water solubility of the conjugate molecule. Please note that modifying the surface amines of biomolecules with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates."

Specifications

Unit Size 100mg, 1000mg
Molecular Weight 1690.00; single compound
Chemical formula C₇₆H₁₅₂O₃₉
CAS 117786-94-4
Purity > 97%
Spacers dPEG® Spacer is 112 atoms and 133.9 Å
Typical solubility properties (for additional information contact Customer Support) Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling -20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.
Shipping Ambient

The post m-dPEG®₃₇-acid appeared first on VectorLabs.

]]>

Description

m-dPEG®37-acid, product number QBD-10909, is a long (112 atoms, 133.9 Å), methyl-capped, discrete chain length polyethylene glycol (dPEG®) spacer that terminates in a propionic acid group. The terminal propionic acid moiety can be coupled directly to free amines using EDC or another carbodiimide. Alternatively, the reactive end can be converted into an active ester that can then be conjugated to free amines. N-hydroxysuccinimide (NHS), 2,3,5,6-tetrafluorophenol (TFP), and 2,3,4,5,6-pentafluorophenol (PFP) typically are used for this purpose.

m-dPEG®37-acid can modify amine-functionalized surfaces (carbon nanotubes, other nanoparticles, quantum dots, etc.) or free amines on biomolecules. When used to coat surfaces or modify biomolecules, m-dPEG®37-acid reduces or eliminates non-specific binding, increases the hydrodynamic volume and water solubility of the conjugate molecule. Please note that modifying the surface amines of biomolecules with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.

Specifications

Unit Size100mg, 1000mg
Molecular Weight1690.00; single compound
Chemical formulaC₇₆H₁₅₂O₃₉
CAS117786-94-4
Purity> 97%
SpacersdPEG® Spacer is 112 atoms and 133.9 Å
Typical solubility properties (for additional information contact Customer Support)Methylene chloride, Acetonitrile, DMAC, DMSO or water.
Storage and handling-20°C; Always let come to room temperature before opening; be careful to limit exposure to moisture and restore under an inert atmosphere; stock solutions can be prepared with dry solvent and kept for several days (freeze when not in use). dPEG® pegylation compounds are generally hygroscopic and should be treated as such. This will be less noticeable with liquids, but the solids will become tacky and difficult to manipulate, if care is not taken to minimize air exposure.
ShippingAmbient



Documents

References

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

The post m-dPEG®₃₇-acid appeared first on VectorLabs.

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