Photocleavable Biotin – VectorLabs https://staging.vectorlabs.com From linker design and synthesis, bioconjugated design and manufacturing, biomolecule labeling and functionalization, and detection system and solutions, our team is here to help you move forward, with impact. Wed, 22 Oct 2025 17:05:58 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.3 https://staging.vectorlabs.com/wp-content/uploads/2024/11/V-favicon-02-100x100.png Photocleavable Biotin – VectorLabs https://staging.vectorlabs.com 32 32 PC Biotin-NHS ester https://staging.vectorlabs.com/products/pc-biotin-nhs-ester/ Tue, 19 Sep 2023 19:28:49 +0000 https://staging.vectorlabs.com/?post_type=product&p=21983 Description

PC Biotin-NHS Ester as a unique amine reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin beads. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).

Specifications

Unit Size 4 x 1 mg, 10 mg, 25 mg, 100 mg
Molecular weight 840.89
Chemical composition C36H52N6O15S
CAS N/A
Solubility DMSO, DMF, DCM, THF, Chloroform
Appearance Slightly yellow amorphos solid to oil
Storage Conditions -20°C. Desiccate
Shipping Conditions Frozen

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Description

PC Biotin-NHS Ester as a unique amine reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin beads. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).

Specifications

Unit Size4 x 1 mg, 10 mg, 25 mg, 100 mg
Molecular weight840.89
Chemical compositionC36H52N6O15S
CASN/A
SolubilityDMSO, DMF, DCM, THF, Chloroform
AppearanceSlightly yellow amorphos solid to oil
Storage Conditions-20°C. Desiccate
Shipping ConditionsFrozen

Documents

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