SpeakEasy Science Blog

The body’s autoimmune response has been leveraged by cancer researchers to propel immunotherapy tools into clinical use. Although the main focus has been on the ability of T-cells to fight cancer cells, the involvement of tumor-infiltrating B-cells is also becoming evident. Tumor-infiltrating B lymphocytes (TIL-Bs) are produced in much higher amounts in various cancers than in healthy tissues, which highlights their positive prognostic value (1). However, their exact role in cancer remains controversial, with the demonstration of both positive and negative impacts.

The body’s autoimmune response has been leveraged by cancer researchers to propel immunotherapy tools into clinical use. Although the main focus has been on the ability of T-cells to fight cancer cells, the involvement of tumor-infiltrating B-cells is also becoming evident. Tumor-infiltrating B lymphocytes (TIL-Bs) are produced in much higher amounts in various cancers than in healthy tissues, which highlights their positive prognostic value (1). However, their exact role in cancer remains controversial, with the demonstration of both positive and negative impacts.

This blog post covers how glycans contribute to cellular mechanisms of health and disease.

This blog post covers how glycans are being used in new frontiers, such as biomarker discovery for cancer and other research fields.

This blog post provides information on the classification, characterization, and applications of glycan-binding proteins.

This article summarizes the considerations for using lectins in glycobiology assay workflows. Although many steps are identical to those in the antibody-integrated workflows, there are subtle but crucial differences.

This article summarizes the considerations for using lectins in glycobiology assay workflows. Although many steps are identical to those in the antibody-integrated workflows, there are subtle but crucial differences.

In this blog post, we will be reviewing everything we know bout lectin structure, classification, and function.

Learn all about glycans, an important building block in many cellular processes.